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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To determine the factors associated with the onset of cannabis use through a systematic review of cohort studies&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">An internet-based search was performed using several keywords and their combinations&#46; Original studies with longitudinal design and the onset of cannabis use as dependent variable&#44; as well as review studies were included&#44; published between January 1980 and May 2004&#46; Methodology quality of the studies was assessed independently by two reviewers&#44; according to pre-established criteria&#44; in order to classify studies in high&#44; mid or low quality&#46; Agreement between reviewers was assessed through kappa coefficient&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 32 relevant studies were identified&#44; of which 13 were of higher quality&#46; Selection bias for the inclusion of consumers at the baseline measurement and lack or insufficient adjustment for confounders were the causes of exclusion&#46; The factors of great evidence related to the onset of cannabis use were masculine sex&#44; consumption of tobacco or alcohol&#44; having a problematic relationship with parents&#44; and cannabis consumption by friends&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">Results highlight the importance of different individual&#44; family and environmental factors on the onset of cannabis use&#46; These must be considered to properly arrange intervention programs focusing on primary prevention among teenagers&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Determinar los factores asociados al inicio del consumo de cannabis a partir de una revisi&#243;n sistem&#225;tica de estudios de cohortes&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; una b&#250;squeda bibliogr&#225;fica informatizada utilizando diversas palabras clave y sus combinaciones&#46; Entre los estudios identificados se seleccionaron los estudios originales de dise&#241;o longitudinal que utilizaran como variable dependiente el inicio de consumo de cannabis&#44; as&#237; como los estudios de revisi&#243;n&#44; publicados entre enero de 1980 y mayo de 2004&#46; Se evalu&#243; la calidad metodol&#243;gica de los estudios mediante 2 revisores&#44; de manera independiente y a partir de unos criterios prestablecidos&#44; clasificando los art&#237;culos en 3 categor&#237;as&#58; alta&#44; intermedia o baja calidad&#46; Se midi&#243; el nivel de concordancia de los revisores a partir del coeficiente kappa&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se identificaron 32 estudios que cumpl&#237;an los criterios de selecci&#243;n&#44; de los cuales 13 fueron determinados de alta calidad&#46; Las causas de exclusi&#243;n fueron el sesgo de selecci&#243;n&#44; por la inclusi&#243;n de consumidores al inicio de la cohorte estudiada&#44; y la falta de ajuste por los potenciales confusores&#46; Los factores que se relacionaron con una mayor evidencia con el inicio del consumo de cannabis fueron el sexo masculino&#44; el consumo de tabaco y alcohol&#44; tener una relaci&#243;n problem&#225;tica con los padres y el consumo de cannabis por parte de los amigos&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los resultados se&#241;alan la importancia de diversos factores individuales&#44; familiares y del entorno en el inicio del consumo de cannabis&#44; que deber&#237;an considerarse de forma conjunta en el abordaje preventivo entre los adolescentes&#46;</p>"
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                      "titulo" => "Psychological and social sequelae of cannabis and other illicit drug use by young people&#58; a systematic review of longitudinal&#44; general population studies"
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                            3 => "I&#46; Crome"
                            4 => "M&#46; Egger"
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                      "titulo" => "Prospective cohort study of cannabis use&#44; predisposition for psychosis&#44; and psychotic symptoms in young people"
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                          "autores" => array:6 [
                            0 => "C&#46; Henquet"
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                            3 => "C&#46; Kaplan"
                            4 => "R&#46; Lieb"
                            5 => "H&#46;U&#46; Wittchen"
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                  "referenciaCompleta" => "European Monitoring Centre for Drugs and Drug&#46; Addiction Annual Report 2004&#58; the state of the drugs problem in the European Union and Norway&#46; Office for Official Publications of the European Communities&#44; Luxembourg&#44; pp&#46; 28-30 &#91;citado 12 Jun 2006&#93;&#46; Disponible en&#58; <a class="elsevierStyleInterRef" href="http://annualreport.emcdda.%20eu.int/download/ar2004-en.pdf">http&#58;&#47;&#47;annualreport&#46;emcdda&#46; eu&#46;int&#47;download&#47;ar2004-en&#46;pdf</a>"
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Vol. 21. Núm. 3.
Páginas 252-260 (mayo - junio 2007)
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Vol. 21. Núm. 3.
Páginas 252-260 (mayo - junio 2007)
Revisión
Open Access
Factors associated with the onset of cannabis use: a systematic review of cohort studies
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Mònica Guxensaa,b, Manel Nebota,
Autor para correspondencia
mnebot@aspb.es

Correspondence: Dr. Manel Nebot. Servei d’Avaluació i Mètodes d’Intervenció. Agència de Salut Pública de Barcelona. Pl. Lesseps, 1. 08015 Bacelona. España.
, Carles Arizaa, Darío Ochoaa,b
a Servei d’Avaluació i Mètodes d’Intervenció, Agència de Salut Pública de Barcelona, España
b Unitat Docent de Medicina Preventiva i Salut Pública IMAS-UPF-ASPB, Barcelona, España
Este artículo ha recibido

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Estadísticas
Abstract
Objective

To determine the factors associated with the onset of cannabis use through a systematic review of cohort studies.

Methods

An internet-based search was performed using several keywords and their combinations. Original studies with longitudinal design and the onset of cannabis use as dependent variable, as well as review studies were included, published between January 1980 and May 2004. Methodology quality of the studies was assessed independently by two reviewers, according to pre-established criteria, in order to classify studies in high, mid or low quality. Agreement between reviewers was assessed through kappa coefficient.

Results

A total of 32 relevant studies were identified, of which 13 were of higher quality. Selection bias for the inclusion of consumers at the baseline measurement and lack or insufficient adjustment for confounders were the causes of exclusion. The factors of great evidence related to the onset of cannabis use were masculine sex, consumption of tobacco or alcohol, having a problematic relationship with parents, and cannabis consumption by friends.

Conclusion

Results highlight the importance of different individual, family and environmental factors on the onset of cannabis use. These must be considered to properly arrange intervention programs focusing on primary prevention among teenagers.

Keywords:
Cannabis
Systematic review
Longitudinal studies
Resumen
Objetivo

Determinar los factores asociados al inicio del consumo de cannabis a partir de una revisión sistemática de estudios de cohortes.

Métodos

Se realizó una búsqueda bibliográfica informatizada utilizando diversas palabras clave y sus combinaciones. Entre los estudios identificados se seleccionaron los estudios originales de diseño longitudinal que utilizaran como variable dependiente el inicio de consumo de cannabis, así como los estudios de revisión, publicados entre enero de 1980 y mayo de 2004. Se evaluó la calidad metodológica de los estudios mediante 2 revisores, de manera independiente y a partir de unos criterios prestablecidos, clasificando los artículos en 3 categorías: alta, intermedia o baja calidad. Se midió el nivel de concordancia de los revisores a partir del coeficiente kappa.

Resultados

Se identificaron 32 estudios que cumplían los criterios de selección, de los cuales 13 fueron determinados de alta calidad. Las causas de exclusión fueron el sesgo de selección, por la inclusión de consumidores al inicio de la cohorte estudiada, y la falta de ajuste por los potenciales confusores. Los factores que se relacionaron con una mayor evidencia con el inicio del consumo de cannabis fueron el sexo masculino, el consumo de tabaco y alcohol, tener una relación problemática con los padres y el consumo de cannabis por parte de los amigos.

Conclusiones

Los resultados señalan la importancia de diversos factores individuales, familiares y del entorno en el inicio del consumo de cannabis, que deberían considerarse de forma conjunta en el abordaje preventivo entre los adolescentes.

Palabras clave:
Cannabis
Revisión sistemática
Estudios longitudinales
El Texto completo está disponible en PDF
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