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    "titulo" => "Incorporación de la metodología geoestadística a la vigilancia de la gripe en una red centinela"
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            "nombre" => "J.J."
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        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Valorar la descripci&#243;n geoestad&#237;stica realizada de los datos de gripe recogidos a trav&#233;s de la Red Centinela Sanitaria de la Comunidad Valenciana &#40;RCSCV&#41; mediante la utilizaci&#243;n del m&#233;todo kriging con la finalidad de evaluar la posibilidad de su incorporaci&#243;n a la vigilancia rutinaria</p> <span class="elsevierStyleSectionTitle">M&#233;todo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se han utilizado los datos de vigilancia de gripe de la RCSCV en tres temporadas gripales &#40;1997-1998&#44; 1998-1999 y 1999-2000&#41;&#44; construy&#233;ndose una matriz de datos de incidencia de gripe geocodificada&#46; La distribuci&#243;n geogr&#225;fica fue estudiada mediante la t&#233;cnica geoestad&#237;stica kriging&#44; que permite estimar la incidencia de la enfermedad en cualquier punto del territorio&#44; a partir de la incidencia observada en unos pocos puntos estrat&#233;gicamente distribuidos&#46; Se elaboraron mapas de curvas de isoincidencia de gripe para cada semana&#46; La valoraci&#243;n de la t&#233;cnica se realiz&#243; mediante validaci&#243;n cruzada&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">En la mayor&#237;a de las semanas&#44; los valores tanto de la desviaci&#243;n est&#225;ndar &#40;DE&#41; reducida&#44; como de la media reducida estuvieron cercanos a los valores considerados &#243;ptimos &#40;0 o 1&#44; respectivamente&#41;&#44; y s&#243;lo en la &#250;ltima temporada se obtuvieron valores de la DE reducida alejados de los considerados como de buen ajuste en 12 de las 20 semanas&#46; La estimaci&#243;n de tasas en todas las temporadas demostr&#243; una coherencia en su distribuci&#243;n espacial&#46; Tambi&#233;n se observ&#243; coherencia en la evoluci&#243;n temporal&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">En la mayor&#237;a de las situaciones los resultados pueden considerarse aceptables&#44; no requiere recursos inform&#225;ticos extraordinarios ni un empleo de tiempo excesivo&#44; y necesita tan s&#243;lo una adaptaci&#243;n anual&#46; Su facilidad de uso lo hace apto para su utilizaci&#243;n como una t&#233;cnica de rutina&#44; pese a que puede mejorarse la precisi&#243;n de las estimaciones&#44; incrementando la complejidad del modelo&#46;</p>"
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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To evaluate geostatistical description of influenza data from the Valencian Sentinel Network &#40;VSN&#41; in Spain using the kriging method and to assess the possibility of incorporating this method into routine surveillance&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We use influenza surveillance data on three influenza seasons &#40;1997-1998&#44; 1998-1999 and 1999-2000&#41; from the VSN to construct a geocodified data matrix of the incidence of this disease&#46; The geographic distribution was studied using the kriging method&#44; which enables estimation of the incidence in a few strategically distributed points&#46; Influenza isoincidence maps for each week were plotted&#46; Cross validation was used to evaluate the method&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">In most of the weeks&#44; the values of reduced standard deviation and reduced mean were close to the optimal values &#40;0 and 1&#44; respectively&#41;&#46; Out of range reduced standard deviation values were found in 12 of 20 weeks in the last season only&#46; The estimation of rates in all three seasons showed coherence in spatial distribution and temporal evolution&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">In most situations the results were acceptable&#46; The method does not requiere extra computer resources or an excessive amount of time and requires only annual adaptation&#46; Becauseit is easy to use&#44; the technique is appropriate for routine use but the accuracy of estimations could be improved by increasing the complexity of the model&#46;</p>"
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                      "titulo" => "The impact of influenza on mortality in the USA"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46; Simonsen"
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                            2 => "D&#46;F&#46; Stroup"
                            3 => "N&#46;H&#46; Arden"
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                        "titulo" => "Options for the control of influenza III"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The impact of influenza epidemics on mortality&#58; introducing a severity index"
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Publ Hlth"
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                        "volumen" => "87"
                        "paginaInicial" => "1944"
                        "paginaFinal" => "1950"
                      ]
                    ]
                  ]
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                      "titulo" => "Impact of respiratory virus infections on persons with chronic underlying conditions"
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                            2 => "R&#46;L&#46; Atmar"
                            3 => "P&#46;A&#46; Piedra"
                            4 => "R&#46;B&#46; Couch"
                          ]
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10659876"
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                    0 => array:2 [
                      "titulo" => "Influenza Pandemic Preparedness Plan&#46; The Role of WHO and Guidelines for National and Regional Planning&#46;"
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                          "colaboracion" => "World Health Organization &#40;WHO&#41;&#46;"
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                      "titulo" => "Experience of European collaboration in influenza surveillance in the winter of 1993-1994"
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                      "Revista" => array:6 [
                        "tituloSerie" => "J Public Health Med"
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                        "paginaInicial" => "133"
                        "paginaFinal" => "142"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8816310"
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                      "titulo" => "Influenza in Madrid&#44; Spain&#44; 1991-92&#58; validity of the sentinel network"
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                        "tituloSerie" => "J Epidemiol Community Health"
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                        "numero" => "Suppl 1"
                        "paginaInicial" => "14"
                        "paginaFinal" => "16"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7561663"
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                      "titulo" => "Programme for the surveillance of influenza in Portugal&#58; results of the period 1990-1996"
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                          "autores" => array:5 [
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                            2 => "A&#46;S&#46; Santos"
                            3 => "M&#46;T&#46; Paixao"
                            4 => "J&#46;M&#46; Falcao"
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                      "Revista" => array:6 [
                        "tituloSerie" => "J Epidemiol Community Health"
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                      "titulo" => "A study of reasons for an increase in acute respiratory tract infections reported by influenza sentinel practices in Germany"
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                  "host" => array:1 [
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                      "Revista" => array:6 [
                        "tituloSerie" => "Epidemiol Infect"
                        "fecha" => "2000"
                        "volumen" => "124"
                        "paginaInicial" => "245"
                        "paginaFinal" => "253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10813150"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Una Red de M&#233;dicos Centinelas en Castilla y Le&#243;n&#58; uso del an&#225;lisis de conglomerados para obtener una poblaci&#243;n representativa"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;T&#46; Vega"
                            1 => "M&#46; Gil"
                            2 => "C&#46; Ruiz"
                            3 => "E&#46; Zapatero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Gac Sanit"
                        "fecha" => "1990"
                        "volumen" => "4"
                        "paginaInicial" => "184"
                        "paginaFinal" => "188"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2286498"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Demanda y prescripci&#243;n del test VIH en atenci&#243;n primaria&#46; Registro de la Red de M&#233;dicos Centinela de Castilla y Le&#243;n en 1991&#44; 1992 y 1993"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;T&#46; Vega"
                            1 => "M&#46; Gil"
                            2 => "C&#46; Ruiz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Gac Sanit"
                        "fecha" => "1996"
                        "volumen" => "10"
                        "paginaInicial" => "25"
                        "paginaFinal" => "33"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8707467"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "La coordinaci&#243;n de las redes centinelas y las nuevas etapas de la vigilancia epidemiol&#243;gica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46;T&#46; Vega"
                            1 => "R&#46; Ram&#237;rez"
                            2 => "M&#46; Larra&#241;aga"
                            3 => "J&#46; Urbina"
                            4 => "O&#46; Zurriaga"
                            5 => "L&#46; Gonz&#225;lez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Gac Sanit"
                        "fecha" => "1998"
                        "volumen" => "12"
                        "numero" => "4"
                        "paginaInicial" => "190"
                        "paginaFinal" => "191"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9793245"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Trastornos de ansiedad&#46; Variabilidad y condicionantes de la actitud terap&#233;utica de los m&#233;dicos de atenci&#243;n primaria"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46;T&#46; Vega"
                            1 => "M&#46; Larra&#241;aga"
                            2 => "O&#46; Zurriaga"
                            3 => "M&#46; Gil"
                            4 => "M&#46; Urtiaga"
                            5 => "J&#46; Calabuig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Aten Primaria"
                        "fecha" => "1999"
                        "volumen" => "24"
                        "paginaInicial" => "569"
                        "paginaFinal" => "578"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10659457"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevenci&#243;n y vigilancia de la gripe en la Comunidad Valenciana&#46; Temporadas 95-96&#44; 96-97&#44; 97-98&#46; Informes de Salud N&#46;&#176; 45&#46;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Pastor"
                            1 => "J&#46;A&#46; Lluch"
                            2 => "O&#46; Zurriaga"
                            3 => "J&#46; Pe&#241;alver"
                            4 => "C&#46; Gimeno"
                            5 => "J&#46; Garc&#237;a- de Lomas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:1 [
                        "serieFecha" => "1999"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Surveillance of influenza in Wales&#58; interpreting sentinel general rates using contemporaneus laboratory data&#46; Opportunities and limitations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;R&#46; Thomas"
                            1 => "R&#46;L&#46; Salmon"
                            2 => "D&#46; Westmoreland"
                            3 => "S&#46;R&#46; Palmer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Epidemiol Community Health"
                        "fecha" => "1998"
                        "volumen" => "52"
                        "numero" => "Suppl 1"
                        "paginaInicial" => "28"
                        "paginaFinal" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Analyzing the geographic spread of diseases&#58; a case study with influenza&#46; Proceedings of the GEOMED&#39;99 - Second International Workshop on Geomedical Systems"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Bonabeau"
                            1 => "L&#46; Toubiana"
                            2 => "A&#46; Flahault"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Par&#237;s&#44; de noviembre de"
                        "fecha" => "1999"
                        "paginaInicial" => "22"
                        "paginaFinal" => "23"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "NASA&#47;FluNet Influenza Project&#46; Proceedings of the GEOMED&#39; 99 - Second International Workshop on Geomedical Systems"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; Viboud"
                            1 => "A&#46; Flahault"
                            2 => "M&#46; Wilson"
                            3 => "M&#46; Myers"
                            4 => "D&#46; Lavanchy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Par&#237;s&#44; de noviembre de"
                        "fecha" => "1999"
                        "paginaInicial" => "22"
                        "paginaFinal" => "23"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:2 [
                        "titulo" => "Disease mapping and risk assesment for public health"
                        "serieFecha" => "1999"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiologic mapping using the &#39;kriging&#39; method&#46; Application to an influenza-like illness epidemic in France"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Carrat"
                            1 => "A&#46;J&#46; Valleron"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Epidemiol"
                        "fecha" => "1992"
                        "volumen" => "135"
                        "paginaInicial" => "1293"
                        "paginaFinal" => "1300"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1626546"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Kriging and cokriging in epidemiology&#58; overview and example&#46; Proceedings of the GEOMED&#39;99 - Second International Workshop on Geomedical Systems"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Carrat"
                            1 => "D&#46; Laurier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "Paris&#44; 22- 23 de noviembre de"
                        "fecha" => "1999"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mining geostatistics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;G&#46; Journel"
                            1 => "C&#46;J&#46; Huijbregts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:1 [
                        "serieFecha" => "1978"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Statistics for spatial data"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "N&#46; Cressie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:1 [
                        "serieFecha" => "1991"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Kriging the local risk of a rare disease from a register of diagnoses"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Webster"
                            1 => "M&#46;A&#46; Oliver"
                            2 => "K&#46;R&#46; Muir"
                            3 => "J&#46;R&#46; Mann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Geografical Analysis"
                        "fecha" => "1994"
                        "volumen" => "26"
                        "paginaInicial" => "168"
                        "paginaFinal" => "185"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevenci&#243;n y vigilancia de la gripe en la Comunidad Valenciana&#46; Temporada 1999-2000"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Pastor"
                            1 => "J&#46;A&#46; Lluch"
                            2 => "O&#46; Zurriaga"
                            3 => "J&#46; Pe&#241;alver"
                            4 => "H&#46; Vanaclocha"
                            5 => "C&#46; Gimeno"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:1 [
                        "serieFecha" => "2000"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The geographical spread of influenza"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Bonabeau"
                            1 => "L&#46; Toubiana"
                            2 => "A&#46; Flahault"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Proc R Soc Lond B Biol Sci"
                        "fecha" => "1998"
                        "volumen" => "265"
                        "paginaInicial" => "2421"
                        "paginaFinal" => "2425"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Health monitoring in sentinel practice networks&#46; Final report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;M&#46; Fleming"
                            1 => "F&#46;G&#46; Schellewis"
                            2 => "W&#46;J&#46; Paget"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:1 [
                        "serieFecha" => "2001"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
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Vol. 16. Núm. 4.
Páginas 324-333 (julio - agosto 2002)
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Vol. 16. Núm. 4.
Páginas 324-333 (julio - agosto 2002)
Open Access
Incorporación de la metodología geoestadística a la vigilancia de la gripe en una red centinela
(Incorporation of geostatistical methodology for influenza surveillance in a sentinel network)
Visitas
5951
J.J. Abellán, O. Zurriaga
Autor para correspondencia
zurriaga_osc@gva.es

Correspondencia: Óscar Zurriaga Lloréns. Servicio de Epidemiología. Dirección General para la Salud Pública. Conselleria de Sanitat. Micer Mascó, 31-33. 46010 Valencia.
, M.A. Martínez-Beneito, J. Peñalver, T. Molins
Servicio de Epidemiología. Dirección General para la Salud Pública. Conselleria de Sanitat. Generalitat Valenciana
Este artículo ha recibido

Under a Creative Commons license
Información del artículo
Resumen
Objetivo

Valorar la descripción geoestadística realizada de los datos de gripe recogidos a través de la Red Centinela Sanitaria de la Comunidad Valenciana (RCSCV) mediante la utilización del método kriging con la finalidad de evaluar la posibilidad de su incorporación a la vigilancia rutinaria

Método

Se han utilizado los datos de vigilancia de gripe de la RCSCV en tres temporadas gripales (1997-1998, 1998-1999 y 1999-2000), construyéndose una matriz de datos de incidencia de gripe geocodificada. La distribución geográfica fue estudiada mediante la técnica geoestadística kriging, que permite estimar la incidencia de la enfermedad en cualquier punto del territorio, a partir de la incidencia observada en unos pocos puntos estratégicamente distribuidos. Se elaboraron mapas de curvas de isoincidencia de gripe para cada semana. La valoración de la técnica se realizó mediante validación cruzada.

Resultados

En la mayoría de las semanas, los valores tanto de la desviación estándar (DE) reducida, como de la media reducida estuvieron cercanos a los valores considerados óptimos (0 o 1, respectivamente), y sólo en la última temporada se obtuvieron valores de la DE reducida alejados de los considerados como de buen ajuste en 12 de las 20 semanas. La estimación de tasas en todas las temporadas demostró una coherencia en su distribución espacial. También se observó coherencia en la evolución temporal.

Conclusiones

En la mayoría de las situaciones los resultados pueden considerarse aceptables, no requiere recursos informáticos extraordinarios ni un empleo de tiempo excesivo, y necesita tan sólo una adaptación anual. Su facilidad de uso lo hace apto para su utilización como una técnica de rutina, pese a que puede mejorarse la precisión de las estimaciones, incrementando la complejidad del modelo.

Palabras clave:
Gripe
Mapas
Vigilancia centinela
Kriging
Abstract
Objectives

To evaluate geostatistical description of influenza data from the Valencian Sentinel Network (VSN) in Spain using the kriging method and to assess the possibility of incorporating this method into routine surveillance.

Methods

We use influenza surveillance data on three influenza seasons (1997-1998, 1998-1999 and 1999-2000) from the VSN to construct a geocodified data matrix of the incidence of this disease. The geographic distribution was studied using the kriging method, which enables estimation of the incidence in a few strategically distributed points. Influenza isoincidence maps for each week were plotted. Cross validation was used to evaluate the method.

Results

In most of the weeks, the values of reduced standard deviation and reduced mean were close to the optimal values (0 and 1, respectively). Out of range reduced standard deviation values were found in 12 of 20 weeks in the last season only. The estimation of rates in all three seasons showed coherence in spatial distribution and temporal evolution.

Conclusions

In most situations the results were acceptable. The method does not requiere extra computer resources or an excessive amount of time and requires only annual adaptation. Becauseit is easy to use, the technique is appropriate for routine use but the accuracy of estimations could be improved by increasing the complexity of the model.

Key words:
Influenza
Maps
Sentinel surveillance
Kriging
El Texto completo está disponible en PDF
Bibliogrífia
[1.]
L. Simonsen, L.B. Schonberger, D.F. Stroup, N.H. Arden, N.J. Cox.
The impact of influenza on mortality in the USA.
Options for the control of influenza III, pp. 26-33
[2.]
L. Simonsen, M.J. Clarke, G.D. Williamson, D.F. Stroup, N.H. Arden, L.B. Schonberger.
The impact of influenza epidemics on mortality: introducing a severity index.
Am J Publ Hlth, 87 (1997), pp. 1944-1950
[3.]
W.P. Glezen, S.B. Greenberger, R.L. Atmar, P.A. Piedra, R.B. Couch.
Impact of respiratory virus infections on persons with chronic underlying conditions.
JAMA, 283 (2000), pp. 499-505
[4.]
World Health Organization (WHO)..
Influenza Pandemic Preparedness Plan. The Role of WHO and Guidelines for National and Regional Planning..
[5.]
D.M. Fleming, J.M. Cohen.
Experience of European collaboration in influenza surveillance in the winter of 1993-1994.
J Public Health Med, 18 (1996), pp. 133-142
[6.]
M.A. Ordobas, B. Zorrilla, P. Arias.
Influenza in Madrid, Spain, 1991-92: validity of the sentinel network.
J Epidemiol Community Health, 49 (1995), pp. 14-16
[7.]
I.M. Falcao, H.R. de Andrade, A.S. Santos, M.T. Paixao, J.M. Falcao.
Programme for the surveillance of influenza in Portugal: results of the period 1990-1996.
J Epidemiol Community Health, 52 (1998), pp. 39-42
[8.]
H. Uphoff.
A study of reasons for an increase in acute respiratory tract infections reported by influenza sentinel practices in Germany.
J Epidemiol Community Health, 52 (1998), pp. 43-45
[9.]
D.M. Fleming, M. Zambon, A.I. Bartelds.
Population estimates of persons presenting to general practitioners with influenzalike illness, 1987-96: a study of the demography of influenza- like illness in sentinel practice networks in England and Wales, and in The Netherlands.
Epidemiol Infect, 124 (2000), pp. 245-253
[10.]
A.T. Vega, M. Gil, C. Ruiz, E. Zapatero.
Una Red de Médicos Centinelas en Castilla y León: uso del análisis de conglomerados para obtener una población representativa.
Gac Sanit, 4 (1990), pp. 184-188
[11.]
A.T. Vega, M. Gil, C. Ruiz.
Demanda y prescripción del test VIH en atención primaria. Registro de la Red de Médicos Centinela de Castilla y León en 1991, 1992 y 1993.
Gac Sanit, 10 (1996), pp. 25-33
[12.]
A.T. Vega, R. Ramírez, M. Larrañaga, J. Urbina, O. Zurriaga, L. González.
La coordinación de las redes centinelas y las nuevas etapas de la vigilancia epidemiológica.
Gac Sanit, 12 (1998), pp. 190-191
[13.]
A.T. Vega, M. Larrañaga, O. Zurriaga, M. Gil, M. Urtiaga, J. Calabuig.
Trastornos de ansiedad. Variabilidad y condicionantes de la actitud terapéutica de los médicos de atención primaria.
Aten Primaria, 24 (1999), pp. 569-578
[14.]
E. Pastor, J.A. Lluch, O. Zurriaga, J. Peñalver, C. Gimeno, J. García- de Lomas, et al.
Prevención y vigilancia de la gripe en la Comunidad Valenciana. Temporadas 95-96, 96-97, 97-98. Informes de Salud N.° 45..
[15.]
D.R. Thomas, R.L. Salmon, D. Westmoreland, S.R. Palmer.
Surveillance of influenza in Wales: interpreting sentinel general rates using contemporaneus laboratory data. Opportunities and limitations.
J Epidemiol Community Health, 52 (1998), pp. 28-31
[16.]
E. Bonabeau, L. Toubiana, A. Flahault.
Analyzing the geographic spread of diseases: a case study with influenza. Proceedings of the GEOMED'99 - Second International Workshop on Geomedical Systems.
París, de noviembre de, (1999), pp. 22-23
[17.]
C. Viboud, A. Flahault, M. Wilson, M. Myers, D. Lavanchy.
NASA/FluNet Influenza Project. Proceedings of the GEOMED' 99 - Second International Workshop on Geomedical Systems.
París, de noviembre de, (1999), pp. 22-23
[18.]
Disease mapping and risk assesment for public health,
[19.]
F. Carrat, A.J. Valleron.
Epidemiologic mapping using the 'kriging' method. Application to an influenza-like illness epidemic in France.
Am J Epidemiol, 135 (1992), pp. 1293-1300
[20.]
F. Carrat, D. Laurier.
Kriging and cokriging in epidemiology: overview and example. Proceedings of the GEOMED'99 - Second International Workshop on Geomedical Systems.
Paris, 22- 23 de noviembre de, (1999),
[21.]
A.G. Journel, C.J. Huijbregts.
Mining geostatistics.
[22.]
N. Cressie.
Statistics for spatial data.
[23.]
R. Webster, M.A. Oliver, K.R. Muir, J.R. Mann.
Kriging the local risk of a rare disease from a register of diagnoses.
Geografical Analysis, 26 (1994), pp. 168-185
[24.]
E. Pastor, J.A. Lluch, O. Zurriaga, J. Peñalver, H. Vanaclocha, C. Gimeno, et al.
Prevención y vigilancia de la gripe en la Comunidad Valenciana. Temporada 1999-2000.
[25.]
E. Bonabeau, L. Toubiana, A. Flahault.
The geographical spread of influenza.
Proc R Soc Lond B Biol Sci, 265 (1998), pp. 2421-2425
[26.]
D.M. Fleming, F.G. Schellewis, W.J. Paget.
Health monitoring in sentinel practice networks. Final report.
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