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Comment. Drug utilization studies. The need to know the indication
Francisco Caamaño
University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
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    "titulo" => "Comment&#46; Drug utilization studies&#46; The need to know the indication"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="p0010" class="elsevierStylePara elsevierViewall">This study deals with the analysis of the factors associated with drug utilization and is therefore a pharmacoepidemiology study and&#44; specifically&#44; a drug utilization study &#40;DUS&#41;<a class="elsevierStyleCrossRef" href="#bb0010"><span class="elsevierStyleSup">1</span></a>&#46;</p><p id="p0015" class="elsevierStylePara elsevierViewall">Although abundant literature on the subject has been published&#44; each new study in this field contributes complementary information&#44; specific to the population studied&#44; since a large proportion of the factors determining drug utilization are sociodemographic&#59; consequently&#44; these studies generally have little external validity&#46;</p><p id="p0020" class="elsevierStylePara elsevierViewall">In the present study&#44; the patients were recruited from health centers and their characteristics&#44; as well as data on drug utilization&#44; were gathered through a questionnaire&#46; Although constructing a primary database can confer researchers with greater freedom and allow the variables gathered specifically for the study to be studied&#44; the potential of secondary sources such as the National Health Survey or the Pharmaceutical Billing Database<a class="elsevierStyleCrossRef" href="#bb0015"><span class="elsevierStyleSup">2</span></a>&#44; the latter in combination with the Health Identification Card&#44; should not be underestimated&#46; In addition to efficiency&#44; both databases are representative of the population in a way that is difficult to achieve in databases generated specifically for a particular study&#46;</p><p id="p0025" class="elsevierStylePara elsevierViewall">However&#44; secondary databases also present major limitations&#46; Pharmaceutical Billing Databases&#44; for example&#44; do not contain information on the indication motivating the drug prescription&#44; making studies of indication-prescription and prescription-indication impossible<a class="elsevierStyleCrossRef" href="#bb0015"><span class="elsevierStyleSup">2</span></a>&#46; And these are&#44; in our opinion&#44; precisely the designs currently required in DUS in Spain&#46;</p><p id="p0030" class="elsevierStylePara elsevierViewall">The Database for Pharmacoepidemiological Research in Primary Care<a class="elsevierStyleCrossRef" href="#bb0010"><span class="elsevierStyleSup">1</span></a> of the Spanish Medication Agency&#44; which includes the participation of 10 autonomous communities and approximately 1&#44;000 physicians&#44; integrates data on signs and symptoms&#44; diagnosis&#44; indication and prescription&#44; in addition to patient characteristics&#46; In the next few years&#44; this database will allow major advances to be made in the DUS performed in primary care&#46;</p><p id="p0035" class="elsevierStylePara elsevierViewall">Importantly&#44; the efficacy of this database will be determined by its accessibility to the distinct research groups&#46; The Spanish Medication Agency should approve the conditions for its use by researchers as soon as possible&#46;</p></span>"
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ISSN: 02139111
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