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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La evaluaci&#243;n de tecnolog&#237;as sanitarias &#40;ETS&#41; es un instrumento basado en la evidencia cient&#237;fica para la toma de decisiones sobre la inclusi&#243;n de avances tecnol&#243;gicos en los sistemas sanitarios&#46; Ahora bien&#44; hay m&#250;ltiples condicionantes y elementos&#44; provenientes tanto de la propia ETS como de profesionales&#44; pol&#237;ticos y de la sociedad&#44; que influyen en que los resultados de la ETS se lleven a cabo&#46; El objetivo de este art&#237;culo es describir los principales elementos que condicionan la aplicaci&#243;n de la ETS en la pr&#225;ctica y su uso en el &#225;mbito cl&#237;nico y en la pol&#237;tica sanitaria&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se ha realizado una b&#250;squeda bibliogr&#225;fica en la base de datos biom&#233;dica PubMed&#46; Se revisaron las referencias seleccionadas&#44; as&#237; como la bibliograf&#237;a adicional y la literatura gris identificada a partir de las referencias&#44; que trataba de temas relacionados con la pr&#225;ctica de la ETS&#46; Los resultados se presentan de manera descriptiva&#44; haciendo un an&#225;lisis de los estudios agrupados por los distintos aspectos de la ETS&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Algunos elementos clave en los que hay posibilidades de mejora son la estandarizaci&#243;n del proceso de evaluaci&#243;n&#44; la descripci&#243;n de la misi&#243;n de la organizaci&#243;n&#44; la priorizaci&#243;n de tecnolog&#237;as a evaluar&#44; la claridad en la presentaci&#243;n de los resultados&#44; la inclusi&#243;n de valores sociales y de costeefectividad&#44; y el aumento de la coordinaci&#243;n internacional&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Para muchos&#44; la raz&#243;n de ser de la ETS es su funci&#243;n expl&#237;cita en la toma de decisiones&#44; aunque esto no est&#225; exento de problemas&#46; Todo parece indicar que el futuro inmediato de la ETS pasa por explicitar los procesos de evaluaci&#243;n y la clara inclusi&#243;n de la ETS en la toma de decisiones&#44; con todo lo que ello supone de priorizaci&#243;n de tecnolog&#237;as&#44; establecimiento de l&#237;mites en cuanto al consumo de recursos econ&#243;micos y vinculaci&#243;n con los procesos pol&#237;ticos&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Health technology assessment &#40;HTA&#41; is a tool based on scientific evidence useful for making decisions about the introduction of technological advances in healthcare systems&#46; However&#44; there are multiple elements that influence the actual use of the results of HTA&#46; These elements are related both to the characteristics of HTA and to the stakeholders involved &#8211;health professionals&#44; politicians&#44; and society&#46; The aim of this article was to describe the main elements that influence the applicability of HTA in practice&#44; as well as the use of HTA in clinical practice and health policy&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A literature search was performed in PubMed&#46; The references retrieved&#44; as well as additional bibliography and gray literature dealing with different aspects of HTA practice identified from the references retrieved&#44; were reviewed&#46; The results are presented descriptively&#44; with analysis of the studies grouped according to the various HTA-related topics&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Key elements that could be improved are standardization of the evaluation process&#44; description of the organization&#8217;s mission&#44; prioritization of the technologies to be assessed&#44; the clarity of the presentation of results&#44; inclusion of values other than scientific evidence&#44; such as social and costeffectiveness values&#44; and increased international coordination&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">For many people&#44; the rationale for HTA is its explicit role in decision making&#44; despite its problems&#46; The immediate future of HTA would seem to include making the assessment process explicit&#44; and the inclusion of HTA in decision making&#46; This entails prioritization of technologies&#44; setting limits on resource allocation and interrelation with political processes&#46;</p>"
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                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:3 [
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                        "fecha" => "2003"
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                        "paginaFinal" => "186"
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                        "paginaInicial" => "144"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9194351"
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                          "autores" => array:1 [
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                        "paginaInicial" => "8"
                        "paginaFinal" => "11"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11704972"
                            "web" => "Medline"
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                      "titulo" => "Setting priorities for the adoption of health technologies on a national level &#8211;the Israeli experience"
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                        "paginaFinal" => "253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10538921"
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                        "tituloSerie" => "Int J Technol Assess Health Care"
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                        "paginaInicial" => "226"
                        "paginaFinal" => "236"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9611899"
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                        "paginaFinal" => "286"
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              "identificador" => "bib0110"
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                            4 => "P&#46; De Jong"
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                        "paginaFinal" => "740"
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                      "titulo" => "The great escape&#63;"
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                        "paginaFinal" => "106"
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                            "web" => "Medline"
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                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12241891"
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                      "titulo" => "Priorisation of health technology assessment&#46; The PATHS model&#58; methods and case studies"
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                            2 => "G&#46; Harper"
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                        "paginaInicial" => "1"
                        "paginaFinal" => "82"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14670218"
                            "web" => "Medline"
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                      "titulo" => "How attractive does a new technology have to be to warrant adoption and utilization&#63;"
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                          "etal" => false
                          "autores" => array:4 [
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                        "tituloSerie" => "Tentative guidelines for using clinical and economic evaluations&#46; Can Med Assoc J"
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                        "paginaFinal" => "1303"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11731399"
                            "web" => "Medline"
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                      "titulo" => "&#191;Qu&#233; es una tecnolog&#237;a sanitaria eficiente en Espa&#241;a&#63;"
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                            3 => "L&#46; Prieto"
                            4 => "J&#46;P&#46; Pinto"
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                        "tituloSerie" => "Gac Sanit"
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                        "paginaInicial" => "334"
                        "paginaFinal" => "343"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12113733"
                            "web" => "Medline"
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                      "titulo" => "Review of international health technology assessment"
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                            0 => "R&#46; Mears"
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                            2 => "P&#46; Littlejohns"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Health technology assessment in Spain"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10932423"
                            "web" => "Medline"
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              "identificador" => "bib0220"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The internationalization of health technology assessment"
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                        "paginaFinal" => "51"
                        "link" => array:1 [
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                          0 => array:2 [
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La introducción de tecnologías en los sistemas sanitarios: del dicho al hecho
The introduction of technologies in health care systems: from saying to doing
Anna García-Altés
Autor para correspondencia
annagarcia@post.harvard.edu

Correspondencia: Fundación Instituto de Investigación en Servicios de Salud.
Fundación Instituto de Investigación en Servicios de Salud. Agència de Salut Pública de Barcelona. Barcelona. España
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    "titulo" => "La introducci&#243;n de tecnolog&#237;as en los sistemas sanitarios&#58; del dicho al hecho"
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      "en" => array:1 [
        "titulo" => "The introduction of technologies in health care systems&#58; from saying to doing"
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            2 => "Medicina basada en la evidencia"
            3 => "Asignaci&#243;n de recursos"
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        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La evaluaci&#243;n de tecnolog&#237;as sanitarias &#40;ETS&#41; es un instrumento basado en la evidencia cient&#237;fica para la toma de decisiones sobre la inclusi&#243;n de avances tecnol&#243;gicos en los sistemas sanitarios&#46; Ahora bien&#44; hay m&#250;ltiples condicionantes y elementos&#44; provenientes tanto de la propia ETS como de profesionales&#44; pol&#237;ticos y de la sociedad&#44; que influyen en que los resultados de la ETS se lleven a cabo&#46; El objetivo de este art&#237;culo es describir los principales elementos que condicionan la aplicaci&#243;n de la ETS en la pr&#225;ctica y su uso en el &#225;mbito cl&#237;nico y en la pol&#237;tica sanitaria&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se ha realizado una b&#250;squeda bibliogr&#225;fica en la base de datos biom&#233;dica PubMed&#46; Se revisaron las referencias seleccionadas&#44; as&#237; como la bibliograf&#237;a adicional y la literatura gris identificada a partir de las referencias&#44; que trataba de temas relacionados con la pr&#225;ctica de la ETS&#46; Los resultados se presentan de manera descriptiva&#44; haciendo un an&#225;lisis de los estudios agrupados por los distintos aspectos de la ETS&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Algunos elementos clave en los que hay posibilidades de mejora son la estandarizaci&#243;n del proceso de evaluaci&#243;n&#44; la descripci&#243;n de la misi&#243;n de la organizaci&#243;n&#44; la priorizaci&#243;n de tecnolog&#237;as a evaluar&#44; la claridad en la presentaci&#243;n de los resultados&#44; la inclusi&#243;n de valores sociales y de costeefectividad&#44; y el aumento de la coordinaci&#243;n internacional&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Para muchos&#44; la raz&#243;n de ser de la ETS es su funci&#243;n expl&#237;cita en la toma de decisiones&#44; aunque esto no est&#225; exento de problemas&#46; Todo parece indicar que el futuro inmediato de la ETS pasa por explicitar los procesos de evaluaci&#243;n y la clara inclusi&#243;n de la ETS en la toma de decisiones&#44; con todo lo que ello supone de priorizaci&#243;n de tecnolog&#237;as&#44; establecimiento de l&#237;mites en cuanto al consumo de recursos econ&#243;micos y vinculaci&#243;n con los procesos pol&#237;ticos&#46;</p>"
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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Health technology assessment &#40;HTA&#41; is a tool based on scientific evidence useful for making decisions about the introduction of technological advances in healthcare systems&#46; However&#44; there are multiple elements that influence the actual use of the results of HTA&#46; These elements are related both to the characteristics of HTA and to the stakeholders involved &#8211;health professionals&#44; politicians&#44; and society&#46; The aim of this article was to describe the main elements that influence the applicability of HTA in practice&#44; as well as the use of HTA in clinical practice and health policy&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A literature search was performed in PubMed&#46; The references retrieved&#44; as well as additional bibliography and gray literature dealing with different aspects of HTA practice identified from the references retrieved&#44; were reviewed&#46; The results are presented descriptively&#44; with analysis of the studies grouped according to the various HTA-related topics&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Key elements that could be improved are standardization of the evaluation process&#44; description of the organization&#8217;s mission&#44; prioritization of the technologies to be assessed&#44; the clarity of the presentation of results&#44; inclusion of values other than scientific evidence&#44; such as social and costeffectiveness values&#44; and increased international coordination&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">For many people&#44; the rationale for HTA is its explicit role in decision making&#44; despite its problems&#46; The immediate future of HTA would seem to include making the assessment process explicit&#44; and the inclusion of HTA in decision making&#46; This entails prioritization of technologies&#44; setting limits on resource allocation and interrelation with political processes&#46;</p>"
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                      "titulo" => "The relationship between technology availability and health care spending"
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                          "autores" => array:5 [
                            0 => "L&#46; Baker"
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                            2 => "J&#46; Geppert"
                            3 => "D&#46; Mishol"
                            4 => "E&#46; Moyneur"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Health Affaires"
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                        "volumen" => "W3"
                        "paginaInicial" => "537"
                        "paginaFinal" => "551"
                      ]
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                    0 => array:2 [
                      "titulo" => "Values and health care reform"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Economic Review"
                        "fecha" => "1996"
                        "volumen" => "86"
                        "paginaInicial" => "1"
                        "paginaFinal" => "24"
                      ]
                    ]
                  ]
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                        "tituloSerie" => "J Economic Perspec"
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                    0 => array:2 [
                      "titulo" => "La evaluaci&#243;n de las tecnolog&#237;as m&#233;dicas"
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                          "autores" => array:1 [
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                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "1995"
                        "volumen" => "10"
                        "paginaInicial" => "581"
                        "paginaFinal" => "585"
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                    ]
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                      ]
                    ]
                  ]
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                        "paginaFinal" => "455"
                        "link" => array:1 [
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                ]
              ]
            ]
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                          "autores" => array:3 [
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                        "tituloSerie" => "BMJ"
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                        "paginaFinal" => "745"
                        "link" => array:1 [
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                      "Revista" => array:2 [
                        "tituloSerie" => "11 de septiembre de"
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                          "autores" => array:3 [
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                        "tituloSerie" => "J Health Serv Res Policy"
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                        "paginaFinal" => "186"
                        "link" => array:1 [
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                      "titulo" => "The role of evidence in health policy&#58; a normative perspective"
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                          "autores" => array:1 [
                            0 => "O&#46; Frithjof Norheim"
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                        "tituloSerie" => "Health Care Analysis"
                        "fecha" => "2002"
                        "volumen" => "10"
                        "paginaInicial" => "309"
                        "paginaFinal" => "317"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12769418"
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                      "titulo" => "Priority setting for health technology assessment&#46; Theoretical considerations and practical approaches&#46; Priority setting Subgroup of the EUR-ASSESS Project"
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                          "autores" => array:5 [
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                            3 => "A&#46; Granados"
                            4 => "D&#46; Banta"
                          ]
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                  "host" => array:1 [
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                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Technol Assess Health Care"
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                        "paginaFinal" => "185"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9194351"
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                      "titulo" => "Implications of the appraisal function of the National Institute for Clinical Excellence"
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                          "autores" => array:1 [
                            0 => "M&#46; Buxton"
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                      "Revista" => array:6 [
                        "tituloSerie" => "Value in Health"
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                        "volumen" => "4"
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                        "paginaFinal" => "11"
                        "link" => array:1 [
                          0 => array:2 [
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              "identificador" => "bib0075"
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                      "titulo" => "Setting priorities for the adoption of health technologies on a national level &#8211;the Israeli experience"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11154787"
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                      "titulo" => "Identification and priority setting for health technology assessment in The Netherlands&#58; actors and activities"
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                          "etal" => false
                          "autores" => array:4 [
                            0 => "W&#46;J&#46; Oortwijn"
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                            2 => "H&#46; Vondeling"
                            3 => "L&#46; Bouter"
                          ]
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                    0 => array:1 [
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                        "tituloSerie" => "Health Policy"
                        "fecha" => "1999"
                        "volumen" => "47"
                        "paginaInicial" => "241"
                        "paginaFinal" => "253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10538921"
                            "web" => "Medline"
                          ]
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                    0 => array:2 [
                      "titulo" => "The use of societal criteria in priority setting for health technology assessment"
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                          "autores" => array:3 [
                            0 => "W&#46;J&#46; Oortwijn"
                            1 => "H&#46; Vondeling"
                            2 => "L&#46; Bouter"
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Technol Assess Health Care"
                        "fecha" => "1998"
                        "volumen" => "14"
                        "paginaInicial" => "226"
                        "paginaFinal" => "236"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9611899"
                            "web" => "Medline"
                          ]
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                    0 => array:2 [
                      "titulo" => "Priority setting in health care&#58; from research to practice&#46; Conference summary"
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                          "autores" => array:2 [
                            0 => "C&#46; Mitton"
                            1 => "C&#46; Donaldson"
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                        "serieFecha" => "2002"
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              "identificador" => "bib0095"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Vitoria"
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                          "colaboracion" => "Priorizaci&#243;n de los temas a evaluar"
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                    0 => array:1 [
                      "LibroEditado" => array:1 [
                        "serieFecha" => "1996"
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              "identificador" => "bib0100"
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                    0 => array:2 [
                      "titulo" => "Prioritzaci&#243; per a la recerca i avaluaci&#243; en serveis sanitaris"
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Aymerich"
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "CAHTA Informatiu"
                        "fecha" => "2001"
                        "volumen" => "22"
                        "paginaInicial" => "18"
                        "paginaFinal" => "20"
                      ]
                    ]
                  ]
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            20 => array:3 [
              "identificador" => "bib0105"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "EUR-ASSESS project subgroup report on dissemination and impact"
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                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Granados"
                            1 => "E&#46; Jonsson"
                            2 => "H&#46;D&#46; Banta"
                            3 => "L&#46; Bero"
                            4 => "A&#46; Bonair"
                            5 => "C&#46; Cochet"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Technol Assess Health Care"
                        "fecha" => "1997"
                        "volumen" => "13"
                        "paginaInicial" => "220"
                        "paginaFinal" => "286"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9194353"
                            "web" => "Medline"
                          ]
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                ]
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            21 => array:3 [
              "identificador" => "bib0110"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Health technology assessment for medical devices in Europe&#46; What must be considered"
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                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Siebert"
                            1 => "L&#46;C&#46; Clauss"
                            2 => "M&#46; Carlisle"
                            3 => "B&#46; Casteels"
                            4 => "P&#46; De Jong"
                            5 => "M&#46; Kreuzer"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Technol Assess Health Care"
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                        "paginaInicial" => "733"
                        "paginaFinal" => "740"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12391964"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0115"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The great escape&#63;"
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                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46; Johri"
                            1 => "P&#46; Lehoux"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Prospects for regulating access to technology through health technology assessment&#46; Int J Technol Assess Health Care"
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                        "paginaInicial" => "179"
                        "paginaFinal" => "193"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12701950"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0120"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "HTA responses and the classic HTA report"
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                            0 => "R&#46; Milne"
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                            2 => "A&#46; Stevens"
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                    ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Public Health Med"
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                        "volumen" => "25"
                        "paginaInicial" => "102"
                        "paginaFinal" => "106"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12848397"
                            "web" => "Medline"
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              "identificador" => "bib0125"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Medical innovation and the critical role of health technology assessment"
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                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Perry"
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                        "tituloSerie" => "JAMA"
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                        "paginaInicial" => "1869"
                        "paginaFinal" => "1872"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10573280"
                            "web" => "Medline"
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              "identificador" => "bib0130"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Health care policy&#58; qualitative evidence and health technology assessment"
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Leys"
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                      "Revista" => array:6 [
                        "tituloSerie" => "Health Policy"
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                        "paginaInicial" => "217"
                        "paginaFinal" => "226"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12941490"
                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "Priority setting for new technologies in medicine&#58; qualitative case study"
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                          "etal" => false
                          "autores" => array:4 [
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                            2 => "M&#46; Giacomini"
                            3 => "L&#46; Pudr&#237;"
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                    0 => array:1 [
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                        "tituloSerie" => "BMJ"
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                        "paginaFinal" => "1318"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11090513"
                            "web" => "Medline"
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              "identificador" => "bib0140"
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                        "tituloSerie" => "Lancet"
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                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13678989"
                            "web" => "Medline"
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                        "paginaFinal" => "919"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10102858"
                            "web" => "Medline"
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                        "paginaFinal" => "944"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11312215"
                            "web" => "Medline"
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                      "Revista" => array:5 [
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                          "autores" => array:4 [
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                            3 => "P&#46;X&#46; Tugwell"
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                        "tituloSerie" => "Tentative guidelines for using clinical and economic evaluations&#46; Can Med Assoc J"
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                          "autores" => array:1 [
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                        "paginaFinal" => "1303"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11731399"
                            "web" => "Medline"
                          ]
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                      "titulo" => "&#191;Qu&#233; es una tecnolog&#237;a sanitaria eficiente en Espa&#241;a&#63;"
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                          "autores" => array:5 [
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                            3 => "L&#46; Prieto"
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                        "paginaFinal" => "343"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12113733"
                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "Review of international health technology assessment"
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                            0 => "R&#46; Mears"
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                            2 => "P&#46; Littlejohns"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Health technology assessment in Spain"
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                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10932423"
                            "web" => "Medline"
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              "identificador" => "bib0220"
              "etiqueta" => "44&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The internationalization of health technology assessment"
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                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46; Menon"
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                    0 => array:1 [
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                        "tituloSerie" => "Int J Technol Assess Health Care"
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                        "paginaInicial" => "45"
                        "paginaFinal" => "51"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8690561"
                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "Co-ordinating health technology assessment in Canada&#58; a European perspective"
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; McDaid"
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                      "Revista" => array:6 [
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                        "fecha" => "2003"
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                        "paginaInicial" => "205"
                        "paginaFinal" => "213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12543533"
                            "web" => "Medline"
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                      "titulo" => "The failings of NICE"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11099269"
                            "web" => "Medline"
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                          "etal" => false
                          "autores" => array:2 [
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                        "link" => array:1 [
                          0 => array:2 [
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                        "volumen" => "327"
                        "paginaInicial" => "1368"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14670877"
                            "web" => "Medline"
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                      "titulo" => "Assessing the impact of health technology assessment"
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                            "web" => "Medline"
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                          0 => array:2 [
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                        "paginaFinal" => "163"
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                        "paginaInicial" => "95"
                        "paginaFinal" => "105"
                        "link" => array:1 [
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                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "The diffusion of new technology&#58; costs and benefits to health care"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;J&#46; Neumann"
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                      "titulo" => "The political dimension in health care technology assessment programs"
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                            0 => "H&#46;D&#46; Banta"
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                        "tituloSerie" => "Int J Technol Assess Health Care"
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                        "paginaFinal" => "123"
                        "link" => array:1 [
                          0 => array:2 [
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