array:24 [
  "pii" => "S0213911107720472"
  "issn" => "02139111"
  "doi" => "10.1157/13110443"
  "estado" => "S300"
  "fechaPublicacion" => "2007-09-01"
  "aid" => "72047"
  "copyright" => "Sociedad Española de Salud Pública y Administración Sanitaria"
  "copyrightAnyo" => "2007"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "fla"
  "cita" => "Gac Sanit. 2007;21:390-6"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2817
    "formatos" => array:3 [
      "EPUB" => 125
      "HTML" => 2271
      "PDF" => 421
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0213911107720484"
    "issn" => "02139111"
    "doi" => "10.1157/13110444"
    "estado" => "S300"
    "fechaPublicacion" => "2007-09-01"
    "aid" => "72048"
    "copyright" => "Sociedad Española de Salud Pública y Administración Sanitaria"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Gac Sanit. 2007;21:397-403"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2534
      "formatos" => array:3 [
        "EPUB" => 122
        "HTML" => 2012
        "PDF" => 400
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
      "titulo" => "Dos m&#233;todos para analizar la evoluci&#243;n de la incidencia de consumo de hero&#237;na y coca&#237;na en Barcelona"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "397"
          "paginaFinal" => "403"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Two methods to analyze trends in the incidence of heroin and cocaine use in Barcelona &#91;Spain&#93;"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Albert S&#225;nchez-Niub&#242;, Ant&#242;nia Domingo-Salvany, Guadalupe G&#243;mez Melis, M&#46; Teresa Brugal, Gianpaolo Scalia-Tomba"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "Albert"
              "apellidos" => "S&#225;nchez-Niub&#242;"
            ]
            1 => array:2 [
              "nombre" => "Ant&#242;nia"
              "apellidos" => "Domingo-Salvany"
            ]
            2 => array:2 [
              "nombre" => "Guadalupe"
              "apellidos" => "G&#243;mez Melis"
            ]
            3 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Teresa Brugal"
            ]
            4 => array:2 [
              "nombre" => "Gianpaolo"
              "apellidos" => "Scalia-Tomba"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213911107720484?idApp=WGSE"
    "url" => "/02139111/0000002100000005/v1_201301241557/S0213911107720484/v1_201301241557/es/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0213911107720460"
    "issn" => "02139111"
    "doi" => "10.1157/13110442"
    "estado" => "S300"
    "fechaPublicacion" => "2007-09-01"
    "aid" => "72046"
    "copyright" => "Sociedad Espa&#241;ola de Salud P&#250;blica y Administraci&#243;n Sanitaria"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Gac Sanit. 2007;21:384-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2331
      "formatos" => array:3 [
        "EPUB" => 129
        "HTML" => 1779
        "PDF" => 423
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
      "titulo" => "Modificaciones en las perspectivas de los m&#233;dicos sobre el registro m&#233;dico electr&#243;nico&#58; investigaci&#243;n cualitativa longitudinal"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "384"
          "paginaFinal" => "389"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Changes in physicians&#8217; attitudes to computerized ambulatory medical record systems&#58; a longitudinal qualitative study"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Adriana Ruth Dawidowski, Luzia Toselli, Daniel Roberto Luna, Pablo Fernando Oberti, Mar&#237;a Aracelli Soto, Fern&#225;n Gonz&#225;lez Bernaldo de Quir&#243;s"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Adriana"
              "apellidos" => "Ruth Dawidowski"
            ]
            1 => array:2 [
              "nombre" => "Luzia"
              "apellidos" => "Toselli"
            ]
            2 => array:2 [
              "nombre" => "Daniel"
              "apellidos" => "Roberto Luna"
            ]
            3 => array:2 [
              "nombre" => "Pablo"
              "apellidos" => "Fernando Oberti"
            ]
            4 => array:2 [
              "nombre" => "Mar&#237;a"
              "apellidos" => "Aracelli Soto"
            ]
            5 => array:2 [
              "nombre" => "Fern&#225;n Gonz&#225;lez"
              "apellidos" => "Bernaldo de Quir&#243;s"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213911107720460?idApp=WGSE"
    "url" => "/02139111/0000002100000005/v1_201301241557/S0213911107720460/v1_201301241557/es/main.assets"
  ]
  "es" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
    "titulo" => "Epidemiolog&#237;a descriptiva de meningitis no meningoc&#243;cicas bacterianas de la provincia de Zaragoza &#40;1999-2004&#41;&#46; Evaluaci&#243;n de su sistema de vigilancia"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "390"
        "paginaFinal" => "396"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Mar&#237;a Pilar Rodrigo Val, Joaqu&#237;n Guimbao, Alberto Vergara, Carmen Varela, Salvador De Mateo, Dionisio Herrera"
        "autores" => array:6 [
          0 => array:4 [
            "nombre" => "Mar&#237;a"
            "apellidos" => "Pilar Rodrigo Val"
            "email" => array:1 [
              0 => "mrodrigo&#64;aragon&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Joaqu&#237;n"
            "apellidos" => "Guimbao"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Alberto"
            "apellidos" => "Vergara"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Carmen"
            "apellidos" => "Varela"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Salvador"
            "apellidos" => "De Mateo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Dionisio"
            "apellidos" => "Herrera"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Programa de Epidemiolog&#237;a Aplicada de Campo&#44; Centro Nacional de Epidemiolog&#237;a&#44; Madrid&#44; Espa&#241;a"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio Provincial de Vigilancia Epidemiol&#243;gica de Zaragoza&#44; Zaragoza&#44; Espa&#241;a"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondencia&#58; M&#46;<span class="elsevierStyleSup">a</span> Pilar Rodrigo Val&#46; Secci&#243;n Vigilancia Epidemiol&#243;gica&#46; Direcci&#243;n General de Salud P&#250;blica&#46; C&#47; Ram&#243;n y Cajal&#44; 68&#46; 50004 Zaragoza&#46; Espa&#241;a&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Descriptive epidemiology of non-meningococcal bacterial meningitis in the province of Saragossa &#91;Spain&#93; from 1999 to 2004&#46; Evaluation of the Epidemiological Surveillance System"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-07-27"
    "fechaAceptado" => "2007-01-29"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec14027"
          "palabras" => array:3 [
            0 => "Vigilancia epidemiol&#243;gica"
            1 => "Meningitis bacterianas"
            2 => "Captura-recaptura"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec14028"
          "palabras" => array:3 [
            0 => "Epidemiological surveillance"
            1 => "Bacterial meningitis"
            2 => "Capture-recapture"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Describir las meningitis no meningoc&#243;cicas bacterianas &#40;MnMB&#41; y evaluar el Sistema de Vigilancia Epidemiol&#243;gica &#40;SVE&#41; en la provincia de Zaragoza entre 1999 y 2004&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se utiliz&#243; el registro de enfermedades de declaraci&#243;n obligatoria &#40;EDO&#41; y el conjunto m&#237;nimo b&#225;sico de datos &#40;CMBD&#41;&#46; Se evalu&#243; el SVE utilizando criterios de los Centers for Disease Control and Prevention&#44; estimando la exhaustividad mediante captura-recaptura&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se notificaron 111 casos de MnMB &#40;62&#44;2&#37; en hombres&#41;&#46; La edad media fue de 40&#44;7 a&#241;os&#46; La mayor proporci&#243;n de casos &#40;16&#44;5&#37;&#41; fue en ni&#241;os menores de 2 a&#241;os&#46; La forma cl&#237;nica en el 81&#44;1&#37; de los casos fue la meningitis&#59; el 70&#44;3&#37; fue diagnosticada por cultivo&#46; Aparecieron <span class="elsevierStyleItalic">Streptococcus</span> en el 54&#37; de los casos &#40;el 82&#37; por <span class="elsevierStyleItalic">S&#46; pneumoniae</span>&#41;<span class="elsevierStyleItalic">&#44;</span> enterobacterias en el 5&#44;4&#37;&#44; <span class="elsevierStyleItalic">Lysteria</span> y <span class="elsevierStyleItalic">Staphylococcus</span> en el 4&#44;5&#37;&#44; <span class="elsevierStyleItalic">Pseudomona aeruginosa</span> en el 1&#44;8&#37;&#44; y <span class="elsevierStyleItalic">Haemophilus influenzae</span> en el 0&#44;9&#37;&#46; La incidencia por 100&#46;000 habitantes fue entre 1&#44;6 en 2004 y 2&#44;6 en 2001&#46; La letalidad fue del 7&#44;3&#37;&#46; La exhaustividad del sistema EDO fue m&#225;xima en el a&#241;o 2001 &#40;del 84&#44;4&#37;&#41;&#46; La exhaustividad conjunta con CMBD fue superior al 85&#37; y la oportunidad fue de 2 d&#237;as&#46; La aceptabilidad del sistema fue buena&#44; ya que el 75&#37; de las variables estaban cumplimentadas en el 97&#37; de las encuestas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Se destaca la relevancia de la evaluaci&#243;n del SVE en funci&#243;n de sus resultados&#46; Las MnMB debidas a <span class="elsevierStyleItalic">S&#46; pneumoniae</span> representan un grupo significativo y su letalidad es elevada&#46; La exhaustividad del SVE en Zaragoza supera el 80&#37;&#44; al considerar EDO y CMBD&#46; La incorporaci&#243;n del CMBD en la vigilancia facilitar&#237;a una aproximaci&#243;n a la incidencia real de algunas EDO&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p class="elsevierStyleSimplePara elsevierViewall">To describe non-meningococcal bacterial meningitis &#40;nMM&#41; and to evaluate the Epidemiological Surveillance System &#40;ESS&#41; in the province of Saragossa &#40;Spain&#41; between 1999 and 2004&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">Information was obtained from the register of diseases subject to mandatory reporting and the Minimum Basic Data Set &#40;MBDS&#41;&#46; The ESS was evaluated by using the Centers for Disease Control and Prevention &#40;CDC&#41; criteria and by estimating the completeness of the system through the capture-recaptu re technique&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">111 cases of nMM were notified &#40;62&#46;2&#37; in males&#41; and the mean age was 40&#46;7 years&#46; The largest proportion of cases &#40;16&#46;5&#37;&#41; occurred in children under 2 years of age&#46; The clinical presentation was meningitis in 81&#46;1&#37;&#46; Diagnosis was through bacterial culture in 70&#46;3&#37;&#46; <span class="elsevierStyleItalic">Streptococcus</span> sp&#46; was found in 54&#37; &#40;82&#37; due to <span class="elsevierStyleItalic">S&#46; pneumoniae</span>&#41;<span class="elsevierStyleItalic">&#44;</span> enterobacteria in 5&#46;4&#37;&#44; <span class="elsevierStyleItalic">Listeria</span> and <span class="elsevierStyleItalic">Staphylococcus</span> in 4&#46;5&#37;&#44; <span class="elsevierStyleItalic">Pseudomonas</span><span class="elsevierStyleItalic">aeruginosa</span> in 1&#46;8&#37;&#44; and <span class="elsevierStyleItalic">Haemophilus</span><span class="elsevierStyleItalic">influenzae</span> in 0&#46;9&#37;&#46; The incidence rate per 100&#44;000 inhabitants was 1&#46;6 in 2004 and 2&#46;6 in 2001&#46; The case fatality was 7&#46;3&#37;&#46; The completeness of the mandatory reporting system reached a peak in 2004 at 84&#46;4&#37;&#46; The combined completeness of the MBDS and the mandatory reporting system was above 85&#37; and timeliness of reporting was 2 days&#46; The acceptability of the system was high since 75&#37; of all variables were complete in 97&#37; of the questionnaires&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">We</span> highlight the importance of evaluation of the ESS&#44; based on its results&#46; nMM due to <span class="elsevierStyleItalic">S&#46; pneumoniae</span> represent an important group of diseases and their case fatality is high&#46; The completeness of the ESS in Saragossa was over 80&#37; when the mandatory reporting system and the MBDS were combined&#46; Incorporating the MBDS into surveillance would facilitate the estimation of the real incidence of various diseases subject to mandatory reporting&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:26 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#201;pid&#233;miologie des m&#233;ningites bact&#233;riennes en France en 2002&#58; M&#233;ningites bact&#233;riennes communautaires"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Perrocheau"
                            1 => "S&#46; Georges"
                            2 => "E&#46; Laurent"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Prat"
                        "fecha" => "2004"
                        "volumen" => "54"
                        "paginaInicial" => "945"
                        "paginaFinal" => "950"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15296270"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aplicaci&#243;n del m&#233;todo captura-recaptura en la evaluaci&#243;n del sistema de vigilancia epidemiol&#243;gica de la enfermedad meningoc&#243;cica en Tenerife &#40;1999-2001&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Izquierdo"
                            1 => "P&#46; Matute"
                            2 => "F&#46; Mart&#237;nez Navarro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Esp Salud P&#250;blica"
                        "fecha" => "2003"
                        "volumen" => "77"
                        "paginaInicial" => "701"
                        "paginaFinal" => "711"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14965062"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Incidence of Haemophilus influenzae type b meningitis during 18 years of vaccine use&#58; observational study using routine hospital data"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46; Peltola"
                            1 => "E&#46; Salo"
                            2 => "H&#46; Sax&#233;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/bmj.38301.657014.79"
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "2005"
                        "volumen" => "330"
                        "paginaInicial" => "18"
                        "paginaFinal" => "19"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15564230"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Meningitis estreptoc&#243;cicas no neumoc&#243;cicas&#58; caracter&#237;sticas cl&#237;nicas y microbiol&#243;gicas de 13 casos"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "Q&#46; Jordano"
                            1 => "V&#46; Falc&#243;"
                            2 => "B&#46; Almirante"
                            3 => "I&#46; Gasser"
                            4 => "C&#46; Pigrau"
                            5 => "A&#46; Pahissa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2003"
                        "volumen" => "120"
                        "paginaInicial" => "739"
                        "paginaFinal" => "741"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Serotype-specific mortality from invasive Streptococcus pneumoniae disease revisited"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46; Martens"
                            1 => "S&#46; Westring"
                            2 => "B&#46; Lundgren"
                            3 => "H&#46;B&#46; Konradsen"
                            4 => "T&#46; Benfield"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1471-2334-4-21"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Infect Dis"
                        "fecha" => "2004"
                        "volumen" => "4"
                        "paginaInicial" => "21"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15228629"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Invasive Pneumococcal infection in Denmark from 1995 to 1999&#58; epidemiology&#44; serotypes and resistance"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "H&#46;B&#46; Konradsen"
                            1 => "M&#46;S&#46; Kaltoft"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Diagn Lab Immunol"
                        "fecha" => "2002"
                        "volumen" => "9"
                        "paginaInicial" => "358"
                        "paginaFinal" => "365"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11874878"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Group a Streptococcal meningitis in adults&#58; report of 41 cases and a review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46; Van de Beek"
                            1 => "J&#46; Gans"
                            2 => "L&#46; Spanjaard"
                            3 => "S&#46; Sela"
                            4 => "M&#46; Vermeulen"
                            5 => "J&#46; Dankert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Infect Dis"
                        "fecha" => "2002"
                        "volumen" => "34"
                        "paginaInicial" => "32"
                        "paginaFinal" => "36"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Bolet&#237;n Oficial del Estado Real Decreto 2210&#47;1995&#44; de 28 de diciembre&#44; por el que se crea la Red Nacional de Vigilancia Epidemiol&#243;gica&#46; BOE n&#46;&#176; 21&#46; 24&#47;1&#47;96&#46;"
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Bolet&#237;n Oficial de Arag&#243;n Decreto 222&#47;96&#44; de 23 de diciembre de 1996&#44; del Gobierno de Arag&#243;n&#44; por el que se regula la Vigilancia Epidemiol&#243;gica en Arag&#243;n&#46; BOA n&#46;&#176; 2&#46; 8&#47;1&#47;97&#46;"
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Bolet&#237;n Oficial del Estado Ley 6&#47;2002&#44; de Salud de Arag&#243;n&#44; de 15 de abril&#46; BOE n&#46;&#176; 122&#46; 21&#47;5&#47;2002&#46;"
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation de l&#8217;exhaustivit&#233; et de la repr&#233;sentativit&#233; d&#8217;un syst&#232;me de surveillance par la m&#233;thode de capture-recapture&#46; Application &#224; la surveillance des infections &#224; m&#233;ningocoque en France en 1989 et 1990&#46;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46; Hubert"
                            1 => "J&#46;C&#46; Desenclos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev &#201;pid&#233;miol Sant&#63; Publique"
                        "fecha" => "1993"
                        "volumen" => "41"
                        "paginaInicial" => "241"
                        "paginaFinal" => "249"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Updated guidelines for evaluating public health surveillance systems&#58; recommendations from the guidelines working group"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Centers for Disease Control and Prevention"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "MMWR"
                        "fecha" => "2001"
                        "volumen" => "50"
                        "paginaInicial" => "1"
                        "paginaFinal" => "35"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18634202"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "World Health Organization&#46; Protocole pour l&#8217;evaluation des syst&#232;mes de surveillance &#233;pidemiologique&#46; WHO&#47;EMC&#47;DIS&#47;97&#46;2"
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "World Health Organization&#46; Protocole d¿evaluation des syst&#232;mes nationaux de surveillance et de risposte concernant les maladies transmissibles&#46; WHO&#47;CDS&#47;CSR&#47;ISR&#47;2001&#46;2"
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Valoraci&#243;n de las asunciones de homogeneidad e independencia en la aplicaci&#243;n del m&#233;todo de captura-recaptura con dos fuentes de informaci&#243;n"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Ballester"
                            1 => "S&#46; P&#233;rez-Hoyos"
                            2 => "D&#46; Ferrer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Gac Sanit"
                        "fecha" => "1997"
                        "volumen" => "11"
                        "paginaInicial" => "150"
                        "paginaFinal" => "151"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9340322"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Incidencia de tuberculosis pulmonar&#58; aplicaci&#243;n del m&#233;todo de captura-recaptura"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46; Ferrer"
                            1 => "F&#46; Ballester"
                            2 => "S&#46; P&#233;rez-Hoyos"
                            3 => "R&#46; Igual"
                            4 => "C&#46; Fluix&#225;"
                            5 => "J&#46; Fullana"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Gac Sanit"
                        "fecha" => "1997"
                        "volumen" => "11"
                        "paginaInicial" => "115"
                        "paginaFinal" => "121"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9340317"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use and limitations of the capture-recapture method in disease monitoring with two dependent sources"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46; Brenner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Epidemiology"
                        "fecha" => "1995"
                        "volumen" => "6"
                        "paginaInicial" => "42"
                        "paginaFinal" => "48"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7888444"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Capture-recapture methods in epidemiology&#58; methods and limitations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46;B&#46; Hook"
                            1 => "R&#46;R&#46; Regal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Epidemiol Rev"
                        "fecha" => "1995"
                        "volumen" => "17"
                        "paginaInicial" => "243"
                        "paginaFinal" => "263"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8654510"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Capture-recapture methods-useful or misleading&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "K&#46; Tilling"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Epidemiol"
                        "fecha" => "2001"
                        "volumen" => "30"
                        "paginaInicial" => "12"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11171841"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Tejero"
                            1 => "P&#46; Asensio"
                            2 => "J&#46;L&#46; Vaquero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2003"
                        "editorial" => "Rev Esp Salud Publica"
                        "editorialLocalizacion" => "Valladolid&#44; Spain"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:3 [
                        "titulo" => "El control de las enfermedades transmisibles"
                        "edicion" => "17a&#46; ed&#46;"
                        "serieFecha" => "2001"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Community- acquired bacterial meningitis in adults&#58; the epidemiology&#44; timing of appropriate antimicrobial therapy&#44; and prognostic factors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;H&#46; Lu"
                            1 => "C&#46;R&#46; Huang"
                            2 => "W&#46;N&#46; Chang"
                            3 => "C&#46;J&#46; Chang"
                            4 => "B&#46;C&#46; Cheng"
                            5 => "P&#46;Y&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Neurol Neurosurg"
                        "fecha" => "2002"
                        "volumen" => "104"
                        "paginaInicial" => "352"
                        "paginaFinal" => "358"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12140104"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of invasive Streptococcus pneumoniae infections in the United States&#44; 1995-1998&#46; Opportunities for prevention in the conjugate vaccine era"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Robinson"
                            1 => "W&#46; Baughman"
                            2 => "G&#46; Rothrock"
                            3 => "N&#46; Barrett"
                            4 => "M&#46; Pass"
                            5 => "C&#46; Lexau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "2001"
                        "volumen" => "285"
                        "paginaInicial" => "1729"
                        "paginaFinal" => "1735"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11277827"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Decisi&#243;n de la Comisi&#243;n de 19 de marzo de 2002&#44; por la que se establecen las definiciones de los casos para comunicar las enfermedades transmisibles a la red comunitaria&#44; de conformidad con la Decisi&#243;n n&#46;&#176; 2119&#47;98&#47;CE del Parlamento Europeo y del Consejo &#91;notificada con el n&#250;mero C &#40;2002&#41; 1043&#93;&#46;"
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bolet&#237;n epidemiol&#243;gico de la Comunidad de Madrid&#58; encuesta sobre su difusi&#243;n y percepci&#243;n entre los m&#233;dicos de atenci&#243;n primaria en el a&#241;o 2000"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Fern&#225;ndez"
                            1 => "B&#46; Zorrilla"
                            2 => "R&#46; Ram&#237;rez"
                            3 => "M&#46;C&#46; &#193;lvarez"
                            4 => "D&#46; L&#243;pez-Gay"
                            5 => "C&#46; Ib&#225;&#241;ez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Esp Salud P&#250;blica"
                        "fecha" => "2002"
                        "volumen" => "76"
                        "paginaInicial" => "347"
                        "paginaFinal" => "357"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12216174"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Invasive pneumococcal disease among infants before and after introduction of pneumococcal conjugate vaccine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Poehling"
                            1 => "T&#46; Talbot"
                            2 => "M&#46; Griffin"
                            3 => "A&#46; Craig"
                            4 => "C&#46; Whitney"
                            5 => "E&#46; Zell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.295.14.1668"
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "2006"
                        "volumen" => "295"
                        "paginaInicial" => "1668"
                        "paginaFinal" => "1674"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16609088"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/02139111/0000002100000005/v1_201301241557/S0213911107720472/v1_201301241557/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "764"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/02139111/0000002100000005/v1_201301241557/S0213911107720472/v1_201301241557/es/main.pdf?idApp=WGSE&text.app=https://gacetasanitaria.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213911107720472?idApp=WGSE"
]
Compartir
Publique en esta revista
Información de la revista
Vol. 21. Núm. 5.
Páginas 390-396 (septiembre - octubre 2007)
Respuestas rápidas
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 21. Núm. 5.
Páginas 390-396 (septiembre - octubre 2007)
Originales
Open Access
Epidemiología descriptiva de meningitis no meningocócicas bacterianas de la provincia de Zaragoza (1999-2004). Evaluación de su sistema de vigilancia
Descriptive epidemiology of non-meningococcal bacterial meningitis in the province of Saragossa [Spain] from 1999 to 2004. Evaluation of the Epidemiological Surveillance System
Visitas
937
María Pilar Rodrigo Vala,
Autor para correspondencia
mrodrigo@aragon.es

Correspondencia: M.a Pilar Rodrigo Val. Sección Vigilancia Epidemiológica. Dirección General de Salud Pública. C/ Ramón y Cajal, 68. 50004 Zaragoza. España.
, Joaquín Guimbaob, Alberto Vergarab, Carmen Varelaa, Salvador De Mateoa, Dionisio Herreraa
a Programa de Epidemiología Aplicada de Campo, Centro Nacional de Epidemiología, Madrid, España
b Servicio Provincial de Vigilancia Epidemiológica de Zaragoza, Zaragoza, España
Este artículo ha recibido

Under a Creative Commons license
Información del artículo
Resumen
Objetivos

Describir las meningitis no meningocócicas bacterianas (MnMB) y evaluar el Sistema de Vigilancia Epidemiológica (SVE) en la provincia de Zaragoza entre 1999 y 2004.

Métodos

Se utilizó el registro de enfermedades de declaración obligatoria (EDO) y el conjunto mínimo básico de datos (CMBD). Se evaluó el SVE utilizando criterios de los Centers for Disease Control and Prevention, estimando la exhaustividad mediante captura-recaptura.

Resultados

Se notificaron 111 casos de MnMB (62,2% en hombres). La edad media fue de 40,7 años. La mayor proporción de casos (16,5%) fue en niños menores de 2 años. La forma clínica en el 81,1% de los casos fue la meningitis; el 70,3% fue diagnosticada por cultivo. Aparecieron Streptococcus en el 54% de los casos (el 82% por S. pneumoniae), enterobacterias en el 5,4%, Lysteria y Staphylococcus en el 4,5%, Pseudomona aeruginosa en el 1,8%, y Haemophilus influenzae en el 0,9%. La incidencia por 100.000 habitantes fue entre 1,6 en 2004 y 2,6 en 2001. La letalidad fue del 7,3%. La exhaustividad del sistema EDO fue máxima en el año 2001 (del 84,4%). La exhaustividad conjunta con CMBD fue superior al 85% y la oportunidad fue de 2 días. La aceptabilidad del sistema fue buena, ya que el 75% de las variables estaban cumplimentadas en el 97% de las encuestas.

Conclusiones

Se destaca la relevancia de la evaluación del SVE en función de sus resultados. Las MnMB debidas a S. pneumoniae representan un grupo significativo y su letalidad es elevada. La exhaustividad del SVE en Zaragoza supera el 80%, al considerar EDO y CMBD. La incorporación del CMBD en la vigilancia facilitaría una aproximación a la incidencia real de algunas EDO.

Palabras clave:
Vigilancia epidemiológica
Meningitis bacterianas
Captura-recaptura
Abstract
Objectives

To describe non-meningococcal bacterial meningitis (nMM) and to evaluate the Epidemiological Surveillance System (ESS) in the province of Saragossa (Spain) between 1999 and 2004.

Methods

Information was obtained from the register of diseases subject to mandatory reporting and the Minimum Basic Data Set (MBDS). The ESS was evaluated by using the Centers for Disease Control and Prevention (CDC) criteria and by estimating the completeness of the system through the capture-recaptu re technique.

Results

111 cases of nMM were notified (62.2% in males) and the mean age was 40.7 years. The largest proportion of cases (16.5%) occurred in children under 2 years of age. The clinical presentation was meningitis in 81.1%. Diagnosis was through bacterial culture in 70.3%. Streptococcus sp. was found in 54% (82% due to S. pneumoniae), enterobacteria in 5.4%, Listeria and Staphylococcus in 4.5%, Pseudomonasaeruginosa in 1.8%, and Haemophilusinfluenzae in 0.9%. The incidence rate per 100,000 inhabitants was 1.6 in 2004 and 2.6 in 2001. The case fatality was 7.3%. The completeness of the mandatory reporting system reached a peak in 2004 at 84.4%. The combined completeness of the MBDS and the mandatory reporting system was above 85% and timeliness of reporting was 2 days. The acceptability of the system was high since 75% of all variables were complete in 97% of the questionnaires.

Conclusion

We highlight the importance of evaluation of the ESS, based on its results. nMM due to S. pneumoniae represent an important group of diseases and their case fatality is high. The completeness of the ESS in Saragossa was over 80% when the mandatory reporting system and the MBDS were combined. Incorporating the MBDS into surveillance would facilitate the estimation of the real incidence of various diseases subject to mandatory reporting.

Key words:
Epidemiological surveillance
Bacterial meningitis
Capture-recapture
El Texto completo está disponible en PDF
Bibliografía
[1.]
A. Perrocheau, S. Georges, E. Laurent.
Épidémiologie des méningites bactériennes en France en 2002: Méningites bactériennes communautaires.
Rev Prat, 54 (2004), pp. 945-950
[2.]
A. Izquierdo, P. Matute, F. Martínez Navarro.
Aplicación del método captura-recaptura en la evaluación del sistema de vigilancia epidemiológica de la enfermedad meningocócica en Tenerife (1999-2001).
Rev Esp Salud Pública, 77 (2003), pp. 701-711
[3.]
H. Peltola, E. Salo, H. Saxén.
Incidence of Haemophilus influenzae type b meningitis during 18 years of vaccine use: observational study using routine hospital data.
[4.]
Q. Jordano, V. Falcó, B. Almirante, I. Gasser, C. Pigrau, A. Pahissa.
Meningitis estreptocócicas no neumocócicas: características clínicas y microbiológicas de 13 casos.
Med Clin (Barc), 120 (2003), pp. 739-741
[5.]
P. Martens, S. Westring, B. Lundgren, H.B. Konradsen, T. Benfield.
Serotype-specific mortality from invasive Streptococcus pneumoniae disease revisited.
BMC Infect Dis, 4 (2004), pp. 21
[6.]
H.B. Konradsen, M.S. Kaltoft.
Invasive Pneumococcal infection in Denmark from 1995 to 1999: epidemiology, serotypes and resistance.
Clin Diagn Lab Immunol, 9 (2002), pp. 358-365
[7.]
D. Van de Beek, J. Gans, L. Spanjaard, S. Sela, M. Vermeulen, J. Dankert.
Group a Streptococcal meningitis in adults: report of 41 cases and a review of the literature.
Clin Infect Dis, 34 (2002), pp. 32-36
[8.]
Boletín Oficial del Estado Real Decreto 2210/1995, de 28 de diciembre, por el que se crea la Red Nacional de Vigilancia Epidemiológica. BOE n.° 21. 24/1/96.
[9.]
Boletín Oficial de Aragón Decreto 222/96, de 23 de diciembre de 1996, del Gobierno de Aragón, por el que se regula la Vigilancia Epidemiológica en Aragón. BOA n.° 2. 8/1/97.
[10.]
Boletín Oficial del Estado Ley 6/2002, de Salud de Aragón, de 15 de abril. BOE n.° 122. 21/5/2002.
[11.]
B. Hubert, J.C. Desenclos.
Evaluation de l’exhaustivité et de la représentativité d’un système de surveillance par la méthode de capture-recapture. Application à la surveillance des infections à méningocoque en France en 1989 et 1990..
Rev Épidémiol Sant? Publique, 41 (1993), pp. 241-249
[12.]
Centers for Disease Control and Prevention.
Updated guidelines for evaluating public health surveillance systems: recommendations from the guidelines working group.
MMWR, 50 (2001), pp. 1-35
[13.]
World Health Organization. Protocole pour l’evaluation des systèmes de surveillance épidemiologique. WHO/EMC/DIS/97.2
[14.]
World Health Organization. Protocole d¿evaluation des systèmes nationaux de surveillance et de risposte concernant les maladies transmissibles. WHO/CDS/CSR/ISR/2001.2
[15.]
F. Ballester, S. Pérez-Hoyos, D. Ferrer.
Valoración de las asunciones de homogeneidad e independencia en la aplicación del método de captura-recaptura con dos fuentes de información.
Gac Sanit, 11 (1997), pp. 150-151
[16.]
D. Ferrer, F. Ballester, S. Pérez-Hoyos, R. Igual, C. Fluixá, J. Fullana.
Incidencia de tuberculosis pulmonar: aplicación del método de captura-recaptura.
Gac Sanit, 11 (1997), pp. 115-121
[17.]
H. Brenner.
Use and limitations of the capture-recapture method in disease monitoring with two dependent sources.
Epidemiology, 6 (1995), pp. 42-48
[18.]
E.B. Hook, R.R. Regal.
Capture-recapture methods in epidemiology: methods and limitations.
Epidemiol Rev, 17 (1995), pp. 243-263
[19.]
K. Tilling.
Capture-recapture methods-useful or misleading?.
Int J Epidemiol, 30 (2001), pp. 12-14
[20.]
S. Tejero, P. Asensio, J.L. Vaquero.
Rev Esp Salud Publica, (2003),
[21.]
El control de las enfermedades transmisibles, 17a. ed.,
[22.]
C.H. Lu, C.R. Huang, W.N. Chang, C.J. Chang, B.C. Cheng, P.Y. Lee, et al.
Community- acquired bacterial meningitis in adults: the epidemiology, timing of appropriate antimicrobial therapy, and prognostic factors.
Clin Neurol Neurosurg, 104 (2002), pp. 352-358
[23.]
K. Robinson, W. Baughman, G. Rothrock, N. Barrett, M. Pass, C. Lexau, et al.
Epidemiology of invasive Streptococcus pneumoniae infections in the United States, 1995-1998. Opportunities for prevention in the conjugate vaccine era.
JAMA, 285 (2001), pp. 1729-1735
[24.]
Decisión de la Comisión de 19 de marzo de 2002, por la que se establecen las definiciones de los casos para comunicar las enfermedades transmisibles a la red comunitaria, de conformidad con la Decisión n.° 2119/98/CE del Parlamento Europeo y del Consejo [notificada con el número C (2002) 1043].
[25.]
S. Fernández, B. Zorrilla, R. Ramírez, M.C. Álvarez, D. López-Gay, C. Ibáñez, et al.
Boletín epidemiológico de la Comunidad de Madrid: encuesta sobre su difusión y percepción entre los médicos de atención primaria en el año 2000.
Rev Esp Salud Pública, 76 (2002), pp. 347-357
[26.]
K. Poehling, T. Talbot, M. Griffin, A. Craig, C. Whitney, E. Zell, et al.
Invasive pneumococcal disease among infants before and after introduction of pneumococcal conjugate vaccine.
JAMA, 295 (2006), pp. 1668-1674
Copyright © 2007. Sociedad Española de Salud Pública y Administración Sanitaria
Descargar PDF
Idiomas
Gaceta Sanitaria
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?