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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Conocer la evoluci&#243;n y la variabilidad en el consumo de los antiinflamarios no esteroideos cl&#225;sicos &#40;AINE&#41; en las &#225;reas de salud de Costa Rica durante el per&#237;odo 2000-2005&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudiaron los siguientes medicamentos&#58; ibuprofeno&#44; indometacina&#44; penicilamina&#44; sulindaco&#44; tenoxican y diclofenaco s&#243;dico&#46; Se utiliz&#243; como medida de consumo la dosis diaria definida por 1&#46;000 habitantes y d&#237;a &#40;DHD&#41;&#44; y en el an&#225;lisis de variabilidad el coeficiente de variaci&#243;n ponderado por el tama&#241;o de poblaci&#243;n &#40;CVw&#41;&#44; el rango extremo&#44; el rango interpercentil&#44; los gr&#225;ficos de puntos y los mapas con categor&#237;as de consumo&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En el per&#237;odo 2000-2005 el consumo de los AINE creci&#243; un 48&#37; y el coste anual se increment&#243; un 184&#37;&#46; Los medicamentos de mayor consumo y participaci&#243;n en el gasto fueron sulindaco e indometacina&#46; El consumo de los AINE vari&#243; entre 0&#44;1 y 60&#44;39 DHD seg&#250;n las &#225;reas de salud&#44; con un CVw del 66&#44;38&#37;&#46; Los medicamento con mayor variabilidad fueron penicilamina &#40;CVw del 449&#44;89&#37;&#41; y tenoxican &#40;CVw del 315&#44;26&#37;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Hay un patr&#243;n geogr&#225;fico diferenciado en el consumo de AINE en el pa&#237;s&#44; y tasas muy diferentes dentro de una misma regi&#243;n&#46; Dos posibles factores asociados a esta variabilidad&#44; seg&#250;n los resultados obtenidos&#44; son la oferta de servicios m&#233;dicos y el porcentaje de poblaci&#243;n mayor de 65 a&#241;os adscrita al &#225;rea de salud&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To determine changing patterns and variability in consumption of classic nonsteroidal anti-inflammatory drugs &#40;NSAIDs&#41; among the health areas in Costa Rica between 2000 and 2005&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">The drugs studied were ibuprofen&#44; indomethacin&#44; penicillamine&#44; sulindac&#44; tenoxicam&#44; and diclofenac sodium&#46; To measure consumption&#44; we used the defined daily dose per 1&#44;000 inhabitants per day &#40;DID&#41;&#46; To analyze variability&#44; the coefficient of variation weighed by the population size &#40;CVw&#41;&#44; extremal ratio&#44; interquartile ratio&#44; dot plot and map graphs were used&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">From 2000-2005&#44; NSAID consumption increased by 48&#37; and the annual cost rose by 184&#37;&#46; The drugs with greatest consumption and participation in cost were sulindac and indomethacin&#46; NSAID consumption varied between 0&#46;1 and 61&#46;8 DID according to health areas&#44; with a CVw of 66&#46;8&#37;&#46; Variability was greatest with penicillamine &#40;CVw<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>449&#46;89&#37;&#41; and tenoxicam &#40;CVw<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>315&#46;26&#37;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Clearly differentiated geographical patterns in NSAID consumption were found in Costa Rica&#44; with very different rates within the same region&#46; According to the results obtained&#44; two factors associated with this variability were the supply of health services and the percentage of the population aged 65 years or more within the catchment area&#46;</p>"
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Vol. 21. Núm. 6.
Páginas 458-464 (noviembre - diciembre 2007)
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Vol. 21. Núm. 6.
Páginas 458-464 (noviembre - diciembre 2007)
Originales
Open Access
Consumo de antiinflamatorios no esteroideos en atención primaria en Costa Rica: evolución y variabilidad geográfica
Consumption of nonsteroidal anti-inflammatory agents in primary care in Costa Rica: changing patterns and geographical variability
Visitas
1060
Melvin Morera Salasa, Amada Aparicio Llanosa, Yanira Xirinachs Salazarb,
Autor para correspondencia
yxirinac@cariari.ucr.ac.ur

Correspondencia: Yarina Xirinachs Salazar. Apartado de correos 332-1000. San José. Costa Rica.
, Patricia Barber Pérezc
a Caja Costarricense de Seguro Social y Proyecto de Investigación en Farmacoeconomía, Universidad de Costa Rica, Costa Rica
b Proyecto de Investigación en Farmacoeconomía, Centro Centroamericano de Población, Posgrado en Economía, Universidad de Costa Rica, Costa Rica
c Departamento de Métodos Cuantitativos, Universidad de Las Palmas Gran Canaria, Las Palmas Gran Canaria, España
Este artículo ha recibido

Under a Creative Commons license
Información del artículo
Resumen
Objetivo

Conocer la evolución y la variabilidad en el consumo de los antiinflamarios no esteroideos clásicos (AINE) en las áreas de salud de Costa Rica durante el período 2000-2005.

Métodos

Se estudiaron los siguientes medicamentos: ibuprofeno, indometacina, penicilamina, sulindaco, tenoxican y diclofenaco sódico. Se utilizó como medida de consumo la dosis diaria definida por 1.000 habitantes y día (DHD), y en el análisis de variabilidad el coeficiente de variación ponderado por el tamaño de población (CVw), el rango extremo, el rango interpercentil, los gráficos de puntos y los mapas con categorías de consumo.

Resultados

En el período 2000-2005 el consumo de los AINE creció un 48% y el coste anual se incrementó un 184%. Los medicamentos de mayor consumo y participación en el gasto fueron sulindaco e indometacina. El consumo de los AINE varió entre 0,1 y 60,39 DHD según las áreas de salud, con un CVw del 66,38%. Los medicamento con mayor variabilidad fueron penicilamina (CVw del 449,89%) y tenoxican (CVw del 315,26%).

Conclusiones

Hay un patrón geográfico diferenciado en el consumo de AINE en el país, y tasas muy diferentes dentro de una misma región. Dos posibles factores asociados a esta variabilidad, según los resultados obtenidos, son la oferta de servicios médicos y el porcentaje de población mayor de 65 años adscrita al área de salud.

Palabras clave:
Antiinflamatorios no esteroideos
Variabilidad en la práctica médica
Dosis diarias definidas por 1.000 habitantes y día
Farmacoeconomía
Economía de la salud
Abstract
Objective

To determine changing patterns and variability in consumption of classic nonsteroidal anti-inflammatory drugs (NSAIDs) among the health areas in Costa Rica between 2000 and 2005.

Methods

The drugs studied were ibuprofen, indomethacin, penicillamine, sulindac, tenoxicam, and diclofenac sodium. To measure consumption, we used the defined daily dose per 1,000 inhabitants per day (DID). To analyze variability, the coefficient of variation weighed by the population size (CVw), extremal ratio, interquartile ratio, dot plot and map graphs were used.

Results

From 2000-2005, NSAID consumption increased by 48% and the annual cost rose by 184%. The drugs with greatest consumption and participation in cost were sulindac and indomethacin. NSAID consumption varied between 0.1 and 61.8 DID according to health areas, with a CVw of 66.8%. Variability was greatest with penicillamine (CVw=449.89%) and tenoxicam (CVw=315.26%).

Conclusions

Clearly differentiated geographical patterns in NSAID consumption were found in Costa Rica, with very different rates within the same region. According to the results obtained, two factors associated with this variability were the supply of health services and the percentage of the population aged 65 years or more within the catchment area.

Key words:
Nonsteroidal anti-inflammatory drugs
Variations in physician practice
Defined daily dose per 1,000 inhabitants per day
Pharmacoeconomics
Health economics
El Texto completo está disponible en PDF
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Copyright © 2007. Sociedad Española de Salud Pública y Administración Sanitaria
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