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    "titulo" => "Serosubtipos de meningococo B causantes de enfermedad invasiva en Cantabria y concordancia con la cepa de la vacuna cubana"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Conocer los serosubtipos de meningococo B causantes de enfermedad invasiva en Cantabria y el porcentaje de concordancia con la cepa de la vacuna cubana VA-Mengoc-BC&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Revisi&#243;n retrospectiva de todos los casos de enfermedad invasiva por meningococo B declarados a trav&#233;s del sistema de Enfermedades de Declaraci&#243;n Obligatoria &#40;EDO&#41; entre el 1 de enero de 1998 y el 28 de febrero de 2003&#44; los aislamientos bacteriol&#243;gicos del Hospital Universitario Marqu&#233;s de Valdecilla y la serosubtipificaci&#243;n hecha en el laboratorio de referencia de Majadahonda&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">De los 117 casos declarados&#44; se identific&#243; el serosubtipo de 79 &#40;67&#44;5&#37;&#41;&#46; La coincidencia con la cepa vacunal cubana fue del 67&#44; el 71 y el 76&#37; en los grupos de edad de 0 a 19 a&#241;os&#44; 18 meses a 19 a&#241;os&#44; y de 4 a 19 a&#241;os&#44; respectivamente&#46; Incluyendo las cepas con protecci&#243;n cruzada&#44; estos porcentajes se elevan al 83&#44; el 83 y el 84&#37;&#44; respectivamente&#44; en los mismos grupos de edad&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El porcentaje de coincidencia con la cepa vacunal cubana y con las cepas heter&#243;logas con protecci&#243;n cruzada es alto&#44; por lo que esta vacuna podr&#237;a ser de utilidad para la situaci&#243;n epidemiol&#243;gica de Cantabria&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To determine the serosubtypes of meningococcus B causing invasive disease in Cantabria and the percentage of agreement with the Cuban vaccine strain&#44; VA-MENGOC-BC&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We performed a retrospective review of all cases of invasive disease due to meningococcus B declared through the Diseases of Mandatory Reporting System between 1st January 1998 and 28th February 2003&#46; The bacteriological isolates of the &#171;Marqu&#233;s de Valdecilla&#187; University Hospital&#44; and the serosubtyping performed in the Majadahonda reference laboratory &#40;Madrid&#44; Spain&#41; were also analyzed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Of the 117 declared cases&#44; serosubtype was identified in 79 &#40;67&#46;5&#37;&#41;&#46; The agreement with the Cuban vaccine strain was 67&#37;&#44; 71&#37; and 76&#37; in the age groups of newborn to 19 years&#44; 18 months to 19 years&#44; and 4 to 19 years&#44; respectively&#46; When strains with cross-protection were included&#44; these percentages increased to 83&#37;&#44; 83&#37; and 84&#37;&#44; respectively&#44; in the same age groups&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The percentage of agreement between the Cuban vaccine strain and heterologous strains with cross-protection was high&#46; Therefore&#44; this vaccine could be useful in Cantabria&#46;</p>"
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