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"titulo" => "Meningococcus B serosubtypes causing invasive disease in Cantabria [Spain] and agreement with the Cuban vaccine strain"
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"resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Conocer los serosubtipos de meningococo B causantes de enfermedad invasiva en Cantabria y el porcentaje de concordancia con la cepa de la vacuna cubana VA-Mengoc-BC.</p> <span class="elsevierStyleSectionTitle">Métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Revisión retrospectiva de todos los casos de enfermedad invasiva por meningococo B declarados a través del sistema de Enfermedades de Declaración Obligatoria (EDO) entre el 1 de enero de 1998 y el 28 de febrero de 2003, los aislamientos bacteriológicos del Hospital Universitario Marqués de Valdecilla y la serosubtipificación hecha en el laboratorio de referencia de Majadahonda.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">De los 117 casos declarados, se identificó el serosubtipo de 79 (67,5%). La coincidencia con la cepa vacunal cubana fue del 67, el 71 y el 76% en los grupos de edad de 0 a 19 años, 18 meses a 19 años, y de 4 a 19 años, respectivamente. Incluyendo las cepas con protección cruzada, estos porcentajes se elevan al 83, el 83 y el 84%, respectivamente, en los mismos grupos de edad.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El porcentaje de coincidencia con la cepa vacunal cubana y con las cepas heterólogas con protección cruzada es alto, por lo que esta vacuna podría ser de utilidad para la situación epidemiológica de Cantabria.</p>"
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"resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To determine the serosubtypes of meningococcus B causing invasive disease in Cantabria and the percentage of agreement with the Cuban vaccine strain, VA-MENGOC-BC.</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We performed a retrospective review of all cases of invasive disease due to meningococcus B declared through the Diseases of Mandatory Reporting System between 1st January 1998 and 28th February 2003. The bacteriological isolates of the «Marqués de Valdecilla» University Hospital, and the serosubtyping performed in the Majadahonda reference laboratory (Madrid, Spain) were also analyzed.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Of the 117 declared cases, serosubtype was identified in 79 (67.5%). The agreement with the Cuban vaccine strain was 67%, 71% and 76% in the age groups of newborn to 19 years, 18 months to 19 years, and 4 to 19 years, respectively. When strains with cross-protection were included, these percentages increased to 83%, 83% and 84%, respectively, in the same age groups.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The percentage of agreement between the Cuban vaccine strain and heterologous strains with cross-protection was high. Therefore, this vaccine could be useful in Cantabria.</p>"
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"etiqueta" => "1."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Sotolongo F y García AM. Estudio de cepas de Neisseria meningitidis circulantes en la Argentina 1991-1993 y ensayo de sueros de vacunados con una vacuna antimeningocócica de origen cubano contra cepas de los diferentes tipos y subtipos causantes de enfermedad"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:4 [
0 => "M. Regueira"
1 => "S. Palmerio"
2 => "M.M. Gutiérrez"
3 => "A. Malberty"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:5 [
"tituloSerie" => "Rev Hosp Niños B Aires"
"fecha" => "1994"
"volumen" => "36"
"paginaInicial" => "242"
"paginaFinal" => "246"
]
]
]
]
]
]
1 => array:3 [
"identificador" => "bib2"
"etiqueta" => "2."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Bactericidal activity in sera from recipients vaccinated with VA-Mengoc-BC against strains of different serotypes and subtypes. En: Pathobiology and immunobiology of Neisseriaceae. Proceedings of the VIII International Pathogenic Neisseria Conference"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "F. Sotolongo"
1 => "O.M. Martínez"
2 => "M.A. Camaraza"
3 => "M. Gutiérrez"
4 => "M.A. Galguera"
5 => "L. Izquierdo"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"LibroEditado" => array:1 [
"serieFecha" => "1994"
]
]
]
]
]
]
2 => array:3 [
"identificador" => "bib3"
"etiqueta" => "3."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Immunogenicity of a serogroup B meningococcal vaccine against multiple Neisseria meningitidis strains in infants"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "S.L. Morley"
1 => "M.J. Cole"
2 => "C.A. Ison"
3 => "M.A. Camaraza"
4 => "F. Sotolongo"
5 => "N. Anwar"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Pediatr Infect Dis J"
"fecha" => "2001"
"volumen" => "20"
"paginaInicial" => "1054"
"paginaFinal" => "1061"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/11734711"
"web" => "Medline"
]
]
]
]
]
]
]
]
3 => array:3 [
"identificador" => "bib4"
"etiqueta" => "4."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Información general sobre la enfermedad meningocócica en Cuba. Vacuna para su prevención y alcance"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:2 [
0 => "L. Almeyda"
1 => "O. Rico"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:5 [
"tituloSerie" => "Rev Hosp Niños B Aires"
"fecha" => "1994"
"volumen" => "36"
"paginaInicial" => "234"
"paginaFinal" => "241"
]
]
]
]
]
]
4 => array:3 [
"identificador" => "bib5"
"etiqueta" => "5."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Studies of serogroup B strains of Neisseria meningitidis: main causal agent of the meningococcal disease in Cuba after 1980. En: Pathobiology and immunobiology of Neisseriaceae. Proceedings of the VIII International Pathogenic Neisseria Conference"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
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1 => "M. Gutiérrez"
2 => "E. Caro"
3 => "L. Rodríguez"
4 => "F. Sotolongo"
5 => "V.G. Sierra"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"LibroEditado" => array:3 [
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"paginaFinal" => "228"
"serieFecha" => "1994"
]
]
]
]
]
]
5 => array:3 [
"identificador" => "bib6"
"etiqueta" => "6."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Epidemiologic & laboratory evaluation of the Cuban meningococcal vaccine BC. Three years of follow up. En: Pathobiology and immunobiology of Neisseriaceae. Proceedings of the VIII International Pathogenic Neisseria Conference"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:4 [
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1 => "C. Campa"
2 => "H. Terry"
3 => "M.L. Echeverry"
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]
]
]
]
"host" => array:1 [
0 => array:1 [
"LibroEditado" => array:3 [
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]
]
]
]
]
]
6 => array:3 [
"identificador" => "bib7"
"etiqueta" => "7."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "The epidemiological impact of antimeningococcal B vaccination in Cuba"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:4 [
0 => "A. Pérez"
1 => "F. Dickinson"
2 => "A. Baly"
3 => "R. Martínez"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Mem Inst Oswaldo Cruz"
"fecha" => "1999"
"volumen" => "94"
"paginaInicial" => "433"
"paginaFinal" => "440"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10445998"
"web" => "Medline"
]
]
]
]
]
]
]
]
7 => array:3 [
"identificador" => "bib8"
"etiqueta" => "8."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Meningococcal conjugate vaccines: new opportunities and new challenges"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:2 [
0 => "M.C.J. Maiden"
1 => "B.G. Spratt"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Lancet"
"fecha" => "1999"
"volumen" => "354"
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"paginaFinal" => "616"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10466659"
"web" => "Medline"
]
]
]
]
]
]
]
]
8 => array:3 [
"identificador" => "bib9"
"etiqueta" => "9."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Vaccine against group B Neisseria meningitidis: protection trial and mass vaccination results in Cuba"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "G.V. Sierra"
1 => "H.C. Campa"
2 => "N.M. Varcacel"
3 => "I.L. García"
4 => "P.L. Izquierdo"
5 => "P.F. Sotolongo"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "NIPH Ann"
"fecha" => "1991"
"volumen" => "14"
"paginaInicial" => "195"
"paginaFinal" => "207"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/1812432"
"web" => "Medline"
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"etiqueta" => "10."
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"titulo" => "Meningococcal disease and VA-Mengoc-BC in minors less than 1 year of age. Cuba 1983 to 1991"
"autores" => array:1 [
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"autores" => array:3 [
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2 => "C. Pereira"
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0 => array:1 [
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"tituloSerie" => "Rev Cubana Med Trop"
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"volumen" => "48"
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"paginaFinal" => "39"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/9768267"
"web" => "Medline"
]
]
]
]
]
]
]
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"titulo" => "VA-Mengoc-BC vaccine: its impact on meningococcal disease in children 1-4 years old"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:2 [
0 => "A. Pérez"
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"tituloSerie" => "Rev Cubana Med Trop"
"fecha" => "1999"
"volumen" => "51"
"paginaInicial" => "189"
"paginaFinal" => "193"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10887587"
"web" => "Medline"
]
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]
]
]
]
]
]
11 => array:3 [
"identificador" => "bib12"
"etiqueta" => "12."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Effectiveness of VA-Mengoc-BC in children from 0 to 5 years of age in Cuba. First year of observation"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:3 [
0 => "O. Rico"
1 => "J.R. Bravo"
2 => "M. Díaz"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Rev Cubana Med Trop"
"fecha" => "1994"
"volumen" => "46"
"paginaInicial" => "94"
"paginaFinal" => "98"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/9768243"
"web" => "Medline"
]
]
]
]
]
]
]
]
12 => array:3 [
"identificador" => "bib13"
"etiqueta" => "13."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Protective efficacy of a serogroup B meningococcal vaccine in Sao Paulo, Brazil"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "J.C. Moraes"
1 => "B.A. Perkins"
2 => "M.C. Camargo"
3 => "N.T. Hidalgo"
4 => "H.A. Barbosa"
5 => "C.T. Sacchi"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Lancet"
"fecha" => "1992"
"volumen" => "340"
"paginaInicial" => "1074"
"paginaFinal" => "1078"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/1357461"
"web" => "Medline"
]
]
]
]
]
]
]
]
13 => array:3 [
"identificador" => "bib14"
"etiqueta" => "14."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "The post-licensing efficacy of VA-Mengoc-BC in children under 6 in Holguín Cuba. The first year of observation"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:3 [
0 => "O. Rico"
1 => "C. Pereira"
2 => "A.A. Fernández"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Rev Cubana Med Trop"
"fecha" => "1995"
"volumen" => "47"
"paginaInicial" => "59"
"paginaFinal" => "64"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/9805070"
"web" => "Medline"
]
]
]
]
]
]
]
]
14 => array:3 [
"identificador" => "bib15"
"etiqueta" => "15."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Immunogenicity of two efficacious outer membrane protein-based serogroup B meningococcal vaccines among young adults in Icelean"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "B.A. Perkins"
1 => "K. Jonsdottir"
2 => "H. Briem"
3 => "E. Griffiths"
4 => "B.D. Plikaytis"
5 => "E.A. Hoiby"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "J Infect Dis"
"fecha" => "1998"
"volumen" => "177"
"paginaInicial" => "683"
"paginaFinal" => "691"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/9498448"
"web" => "Medline"
]
]
]
]
]
]
]
]
15 => array:3 [
"identificador" => "bib16"
"etiqueta" => "16."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "The hyperferremic mouse model for the evaluation of the effectiveness of VA-Mengoc-BC against Neisseria meningitidis B clinical isolates"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:6 [
0 => "S. Sifontes"
1 => "J.F. Infante"
2 => "P. Pérez"
3 => "E. Caro"
4 => "G. Sierra"
5 => "C. Campa"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:7 [
"tituloSerie" => "Arch Med Res"
"fecha" => "1997"
"volumen" => "28"
"paginaInicial" => "41"
"paginaFinal" => "45"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/9078586"
"web" => "Medline"
]
]
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"pii" => "S0091674901739437"
"estado" => "S300"
"issn" => "00916749"
]
]
]
]
]
]
]
16 => array:3 [
"identificador" => "bib17"
"etiqueta" => "17."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Immunogenicity of 2 serogroup B outer-membrane protein meningococcal vaccines: a randomized controlled trial in Chile"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "J.W. Tappero"
1 => "R. Lagos"
2 => "A.M. Ballesteros"
3 => "B. Plikaytis"
4 => "D. Williams"
5 => "J. Dykes"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "JAMA"
"fecha" => "1999"
"volumen" => "281"
"paginaInicial" => "1520"
"paginaFinal" => "1527"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10227322"
"web" => "Medline"
]
]
]
]
]
]
]
]
17 => array:3 [
"identificador" => "bib18"
"etiqueta" => "18."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Seroprevalencia de anticuerpos bactericidas frente al meningococo C en Cantabria 10 meses después de la campaña de vacunación"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:2 [
0 => "A. González de Aledo"
1 => "J. García Merino"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:5 [
"tituloSerie" => "Rev Esp Salud Pub"
"fecha" => "1998"
"volumen" => "72"
"paginaInicial" => "365"
"paginaFinal" => "367"
]
]
]
]
]
]
18 => array:3 [
"identificador" => "bib19"
"etiqueta" => "19."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Perpectivas de la vacuna frente al meningococo B"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:1 [
0 => "J.A. Navarro Alonso"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:5 [
"tituloSerie" => "Vacunas"
"fecha" => "2000"
"volumen" => "1"
"paginaInicial" => "10"
"paginaFinal" => "13"
]
]
]
]
]
]
]
]
]
]
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