Información de la revista
Vol. 6. Núm. 28.
Páginas 30-39 (enero - febrero 1992)
Respuestas rápidas
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 6. Núm. 28.
Páginas 30-39 (enero - febrero 1992)
Open Access
Metaanálisis en epidemiología, (segunda parte): métodos cuantitativos
Metha-Analysis in Epidemiology (Second Part): Quantitative Methods
Visitas
4952
Miguel Delgado Rodríguez*,**,***,****, Maria Sillero Arenas**,***, Ramón Gálvez Vargas*,***
* Cátedra de Medicina Preventiva, Facultad de Medicina
** Hospital «Virgen de las Nieves» Granada
*** Delegación Provincial de Salud y Consumo Jaén
Este artículo ha recibido

Under a Creative Commons license
Información del artículo
Resumen

El objetivo del presente trabajo es poner al alcance del lector interesado en el tema los principales métodos cuantitativos del metaanáiísis que se han aplicado en el terreno sanitario, haciéndose especial hincapié en los más utilizados. Se ofrece también un pequeño resumen de los métodos más difundidos para determinar la presencia de un sesgo de publicación Se discuten las ventajas e inconvenientes de cada procedimiento detallado.

Palabras clave:
Metaanálisis
Métodos epidemiológicos
Revisiones
Summary

The main goal of this paper is to offer an introduction to the quantitative methods of meta-analysis used in epidemiology/public health, emphasizing on the most widespread used. We give also a brief reference of the methods to recognize publication bias. The limitations and advantages of the methods commented on are discussed.

Key words:
Metha-analysis
Epidemiological methods
Reviews
El Texto completo está disponible en PDF
Bibliogrífia
[1.]
R.J. Light, D.B. Pillemer.
Summing up. The science of reviewing research.
Harvard University Press, (1984),
[2.]
L.V. Hedges, I. Okin.
Statistical methods for meta analysis.
Academic Press, (1985),
[3.]
M. Jenicek.
Meta-analyse en médicine.
Edisem, (1987),
[4.]
S. Greenland.
Quantitative methods in the review of epidemiologic literature.
Epidemiol Rev, 9 (1987), pp. 1-30
[5.]
D.L. DeMets.
Methods for combining randomized clinical trials: strengths and limitations.
Stat Med, 6 (1987), pp. 341-348
[6.]
J.-P. Boissel, J. Blanchard, E. Panak, J.-C. Peyrieux, H. Sacks.
Considerations for the meta-analysis of randomized clinical trials (Summary of a panel discussion).
Controlled Clin Trials, 10 (1989), pp. 254-281
[7.]
S.N. Goodman.
Meta-analysis and evidence.
Controlled Clin Trials, 10 (1989), pp. 188-204
[8.]
H.L. Needleman, C.A. Gatsonis.
Low-level exposure and the IQ of children. A meta-analysis of modern studies.
JAMA, 263 (1990), pp. 673-678
[9.]
B. Woolf.
On estimating the relationship between blood group and disease.
Ann Human Genet, 19 (1955), pp. 251-253
[10.]
M. Delgado-Rodríguez, M. Sillero-Arenas, R. Rodríguez-Contreras, R. López, R. Gálvez-Vargas.
Oral contraceptives and breast cancer. A meta-analysis.
Rev Epidém Santé Publ, 39 (1991), pp. 165-181
[11.]
M. Sillero Arenas.
Metaanálisis de la relación entre los contraceptivos orales y los cánceres de mama y cuello uterino.
Universidad de Granada, (1989),
[12.]
M. Delgado-Rodríguez, M. Sillero-Arenas, R. Rodríguez-Contreras, R. Martín Moreno, J.M. Gálvez-Vargas.
Oral contraceptives and cancer of the cervix uteri. A meta-analysis.
Eur J Epidemiol, (1991),
[13.]
M. Sillero-Arenas, M. Delgado-Rodríguez, R. Rodíguez-Contreras, A. Bueno-Cavanillas, R. Gálvez-Vargas.
Hormone replacement therapy and breast cancer. A meta-analysis.
Obstet Gynecol, 79 (1992), pp. 276-304
[14.]
J.L. Fleiss.
Statistical methods for rates and proportions.
2nd ed., Wiley-Interscience, (1981),
[15.]
D.G. Kleinbaum, L.L. Kupper, H. Morgenstern.
Epidemiologic Research.
Lifetime Learning Publications, (1982),
[16.]
K.J. Rothman.
Modern Epidemiology.
Little, Brown & Co., (1986),
[17.]
O.S. Miettinen.
Estimability and estimation in case-referent studies.
Am J Epidemiol, 103 (1976), pp. 226-235
[18.]
B. Trock, E. Lanza, P. Greenwald.
Dietary fiber, vegetables, and colon cancer: critical review and meta-analyses of the epidemiologic evidence.
JNCI, 82 (1990), pp. 650-661
[19.]
S.W. Duffy, T.E. Rohan, D.G. Altman.
A method for combining matched and unmatched binary data.
Am J Epidemiol, 130 (1989), pp. 371-377
[20.]
S. Yusuf, R. Peto, J. Lewis, R. Collins, P. Sleight.
Beta blockade during and after myocardial infarction: an overview of the randomized trials.
Prog Cardiovas Dis, (1985), pp. 335-371
[21.]
R. Peto, M.C. Pike, P. Armitage, N.E. Breslow, D.R. Cox, S.V. Howard, N. Mantel, K. McPherson, J. Peto, P.G. Smith.
Design and analysis of randomized clinical trials requiring prolonged observations of each patient. II. Analysis and examples.
Br J Cancer, 35 (1977), pp. 1-39
[22.]
D. Zucker, S. Yusuf.
The likelihood ratio versus the p value in meta-analysis; where is the evidence?.
Controlled Clin Trials, 10 (1989), pp. 205-208
[23.]
R. DerSimonian, N. Laird.
Meta-analysis in clinical trials.
Control Clin Trials, 7 (1986), pp. 177-188
[24.]
R.E. Dales, R.M. Stark, S. Raman.
Computed tomography to stage lung cancer.
Am Rev Resp Dis, 141 (1990), pp. 1096-1101
[25.]
E.S. Gilbert, S.A. Fry, L.D. Friggs, G.L. Volez, D.L. Cragle, G.R. Petersen.
Methods for anayzing combined data from studies of workers exposed to low doses ol radiation.
Am J Epidemiol, 131 (1990), pp. 917-927
[26.]
M.P. Longnecker, J.A. Berlin, M.J. Orza, T.C. Chalmers.
A meta-analysis of alcohol consumption in relation to risk of breast cancer.
JAMA, 260 (1988), pp. 652-656
[27.]
M. Delgado Rodríguez, M. Gómez Olmedo, M.A. Fernández Sierra.
Metaanálisis de la prevalencia de la úlcera péptica en relación al consumo de tabaco (Carta al Director).
Med Clín (Barc), 95 (1990), pp. 60
[28.]
A.M. Walker, J.M. Martín-Moreno, F. Rodríguez Artalejo.
Odd man out: a graphical approach to meta analysis.
Am J Public Health, 78 (1988), pp. 961-966
[29.]
T.D. Spector, M.C. Hochberg.
The protective effect of the oral contraceptive pill on reumathoid arthritis: an overview of the analytical epidemiological studies using meta-analysis.
J Clin Epidemiol, 43 (1990), pp. 1221-1230
[30.]
S.L. Rifat.
Graphic representations of effect estimates: an example from a meta-analytic review.
J Clin Epidemiol, 43 (1990), pp. 1267-1271
[31.]
R. Rodríguez-Coronado, M. Delgado Rodríguez, M. Sillero Arenas, P. Lardelli Claret, R. Gálvez Vargas.
Contraceptivos orales y cáncer de cuello uterino: análisis del poder de la asociación.
Rev San Hig Públ, 65 (1991), pp. 25-38
[32.]
M. Delgado Rodríguez, M. Sillero Arenas, R. Rodríguez-Contreras, A. Bueno Cavanillas, J.M. Martín Moreno, R. Gálvez Vargas.
Anticonceptivos orales y cáncer de mama: análisis de la potencia estadistica de asociación.
Gaceta Sanitaria, 5 (1991), pp. 59-67
[33.]
R. Gálvez Vargas, M. Delgado Rodríguez, et al.
Epidemiologíal experimental.
Medicina preventiva y salud pública, 8ª edición, pp. 125-134
[34.]
K.J. Rothman.
Epidemiologic methods in clinical trials.
Cancer, 39 (1977), pp. 1771-1775
[35.]
D.A. Henry, D.L. O' Connell.
Effects of fibrinolytic inhibitors on mortality from upper gastrointestinal haemorrhage.
Br Med J, 298 (1989), pp. 1142-1146
[36.]
G.T. O' Connor, J.E. Buring, S. Yusuf, S.Z. Goldhaber, E.M. Olmstead, R.S. Paffenbarger Jr., C.H. Hennekens.
An overview of randomized trials of rehabilitation with exercise after myocardial infarction.
Circulation, 80 (1989), pp. 234-244
[37.]
J.A. Berlin, N.M. Laird, H.S. Sacks, T.C. Chalmers.
A comparison of statistical methods for combining event rates from clinical trials.
Stat Med, 8 (1989), pp. 141-151
[38.]
R. Gálvez Vargas, M. Delgado Rodríguez.
Estudios de cohortes.
Medicina preventiva y salud pública, 8º edición, pp. 105-114
[39.]
D.A. Savitz, A.E. Baron.
Estimating and correcting for confounder misclassification.
Am J Epidemiol, 129 (1989), pp. 1062-1071
[40.]
U.R. Abel, L. Edler.
A pitfall in the meta-analysis of hazard ratios.
Controlled Clin Trials, 9 (1988), pp. 149-151
[41.]
J.L. Fleiss, A.J. Gross.
Meta-analysis in epidemiology, with special reference to studies of the association between exposure to environmental tobacco smoke and lung cancer: a critique.
J Clin Epidemiol, 44 (1991), pp. 127-139
[42.]
J.P. Vandenbroucke.
Passive smoking and lung cancer: a publication bias?.
Br Med J, 296 (1988), pp. 391-392
[43.]
A.C. Tersmette, J.A. Offerhaus, K.W.F. Tersmette, F.M. Giardello, G.W. Moore, G.M.J. Tytgat, J.P. Vandenbroucke.
Meta-analysis of the risk of gastric stump cancer: detection of high risk patients subsets for stomach cancer after remote partial gastrectomy for benign conditions.
Cancer Res, 50 (1990), pp. 6486-6489
[44.]
R. Rosenthal.
Meta-analytic procedures for social research.
Beverly Hills, pp. 345
[45.]
R.J. Ozminkowski, P.M. Wortman.
Inborn/outborn status and neonatal survival: a meta-analysis of non-randomized studies.
Stat Med, 7 (1988), pp. 1207-1221
Copyright © 1992. Sociedad Española de Salud Pública y Administración Sanitaria
Descargar PDF
Idiomas
Gaceta Sanitaria
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?