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        "titulo" => "Incidence of type 2 diabetes and its diagnosis process in the decade 1991-2000 in a primary health care centre"
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            2 => "Prevalencia"
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            4 => "Atenci&#243;n primaria"
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        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento y objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Conocer la incidencia anual y los motivos de diagn&#243;stico de la diabetes mellitus tipo 2 &#40;DM2&#41; en el per&#237;odo 1991-2000&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio longitudinal retrospectivo&#46; Revisi&#243;n de las historias cl&#237;nicas de todos los nuevos casos de DM2 registrados en un centro de salud urbano durante 10 a&#241;os&#46; C&#225;lculo de la prevalencia e incidencia anuales en la poblaci&#243;n mayor de 14 a&#241;os&#46; An&#225;lisis de las tendencias temporales y periodicidad en la incidencia de DM2 &#40;mensual&#44; estacional y anual&#41; mediante modelos ARIMA &#40;Box-Jenkins&#41;&#44; modelo param&#233;trico de regresi&#243;n de Poisson y modelos semiparam&#233;tricos &#40;GAM&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se identificaron 598 nuevos casos de DM2 &#40;edad media &#91;DE&#93;&#44; 59&#44;7 &#91;11&#44;4&#93; a&#241;os&#59; 51&#44;3&#37; mujeres&#41;&#46; Los factores de riesgo cardiovascular m&#225;s frecuentes fueron la obesidad &#40;58&#44;5&#37;&#41; y la hipertensi&#243;n arterial &#40;68&#44;2&#37;&#41;&#46; Los principales motives de diagn&#243;stico fueron&#58; hiperglucemias previas &#40;64&#44;7&#37;&#41; y la aplicaci&#243;n de protocolos de otros factores de riesgo cardiovascular &#40;12&#44;4&#37;&#41;&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">La incidencia anual fue de 37&#44;9 por 10&#46;000 personas &#40;intervalo de confianza &#91;IC&#93; del 95&#37;&#44; 34&#44;9-40&#44;9&#41;&#44; sin diferencias significativas entre ambos sexos&#46; La prevalencia de DM2 al principio y al final del estudio fue del 4&#44;4&#37; &#40;IC del 95&#37;&#44; 2&#44;0-4&#44;8&#41; y el 5&#44;5&#37; &#40;IC del 95&#37;&#44; 5&#44;2-5&#44;9&#41; &#40;un 25&#37; de incremento relativo&#41;&#44; sin que el an&#225;lisis de tendencias mostrara un incremento progresivo de la incidencia&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La incidencia observada es superior a la descrita en otros estudios&#46; El incremento de la prevalencia no se relaciona con un incremento progresivo de la incidencia&#46; Los motivos de diagn&#243;stico m&#225;s frecuentes fueron el seguimiento de hiperglucemias previas y la aplicaci&#243;n de protocolos de otros factores de riesgo cardiovascular&#46; Este hecho parece indicar un diagn&#243;stico precoz que podr&#237;a beneficiar a estos pacientes&#46;</p>"
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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Background and objective</span><p class="elsevierStyleSimplePara elsevierViewall">To determine the annual incidence and reasons for diagnosing type 2 diabetes mellitus &#40;T2DM&#41; from 1991 to 2000&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">We performed a retrospective&#44; longitudinal study&#46; The clinical records of all new cases of T2DM registered in an urban primary care center over a 10-year period were reviewed&#46; The annual incidence and prevalence in the population aged more than 14 years old were calculated&#46; Statistical analyses of temporal trends and periodicity &#40;monthly&#44; seasonal and annual&#41; were performed with ARIMA models &#40;Box-Jenkins&#41;&#44; Poisson parametrical regression and semiparametrical &#40;GAM&#41; models&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">There were 598 true new cases of T2DM &#40;mean age &#91;SD&#93;&#58; 59&#46;7 &#91;11&#46;4&#93; years&#59; 51&#46;3&#37; women&#41;&#46; The most frequent associated cardiovascular risk factors were obesity &#40;58&#46;5&#37;&#41; and hypertension &#40;68&#46;2&#37;&#41;&#46; The main reasons for diagnosing T2DM were the presence of previous hyperglycemia &#40;64&#46;7&#37;&#41; and the application of protocols for other cardiovascular risk factors &#40;12&#46;4&#37;&#41;&#46;The annual incidence was 37&#46;9 per 10&#44;000 persons &#40;95&#37; CI&#44; 34&#46;9-40&#46;9&#41; with no differences between sexes&#46; The prevalence of T2DM at the beginning and end of the study period was 4&#46;4 &#40;95&#37; CI&#44; 2&#46;0-4&#46;8&#41; and 5&#46;5&#37; &#40;95&#37; CI&#44; 5&#46;2-5&#46;9&#41; &#40;25&#37; relative increase&#41;&#46; There was no significant temporal trend in the incidence of T2DM over the years&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The observed incidence of T2DM is high compared with that reported in other studies&#46; The increase in prevalence was not related to a progressive increase in the incidence&#46; The most frequent reasons for diagnosing T2DM were previous hyperglycemia and the application of protocols for other cardiovascular risk factors&#46; This finding seems to be related to an early diagnosis and could benefit these patients&#46;</p>"
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                      "titulo" => "Global prevalence of diabetes&#58; estimates for the year 2000 and projections for 2030"
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                      "titulo" => "Impact of incident diabetes and incident nonfatal cardiovascular disease on 18-year mortality&#58; the Multiple Risk Factor Intervention Trial experience"
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                      "titulo" => "Improvement in quality of diabetes care in primary health care centres&#58; a seven years experience"
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                        "titulo" => "Proceedings of the 38th annual meeting of the European Association for the Study of Diabetes"
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                        "fecha" => "2002"
                        "conferencia" => "Budapest&#44; 1-5 de septiembre de 2002"
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                      "titulo" => "Lucioni C&#59; CODE-2 Advisory Board Assessing the impact of complications on the costs of type II diabetes"
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                        "tituloSerie" => "Diabetologia"
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                      "titulo" => "Impacto de la diabetes mellitus tipo 2 en la calidad de vida de los pacientes tratados en las consultas de atenci&#243;n primaria en Espa&#241;a"
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