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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El proyecto INMA &#40;Infancia y Medio Ambiente&#41; es una red de investigaci&#243;n cooperativa que tiene como objetivos estudiar los efectos del medio ambiente y la dieta en el desarrollo fetal e infantil&#46; El objetivo de este art&#237;culo es presentar el protocolo de exposici&#243;n a contaminantes atmosf&#233;ricos durante el embarazo y desarrollo prenatal y neonatal en el proyecto INMA&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">La informaci&#243;n para la evaluaci&#243;n de la exposici&#243;n a contaminaci&#243;n atmosf&#233;rica durante el embarazo se basa en mediciones de contaminantes atmosf&#233;ricos en el exterior &#40;di&#243;xido de nitr&#243;geno &#91;NO<span class="elsevierStyleInf">2</span>&#93;&#44; compuestos org&#225;nicos vol&#225;tiles &#91;COV&#93;&#44; ozono&#44; part&#237;culas &#91;PM<span class="elsevierStyleInf">10</span>&#44; PM<span class="elsevierStyleInf">2&#44;5</span>&#93; y su composici&#243;n &#91;hidrocarburos arom&#225;ticos polic&#237;clicos&#93;&#41;&#44; medici&#243;n de contaminantes de exposici&#243;n individual &#40;en el interior de la vivienda y captadores personales &#91;COV y NO<span class="elsevierStyleInf">2</span>&#93;&#41;&#44; determinaci&#243;n de un marcador biol&#243;gico de exposici&#243;n a hidrocarburos &#40;1-hidroxipireno&#41;&#44; en informaci&#243;n recogida mediante cuestionarios y en la utilizaci&#243;n de sistemas de informaci&#243;n geogr&#225;fica&#46; Esta informaci&#243;n permite elaborar &#237;ndices de exposici&#243;n individual a contaminaci&#243;n atmosf&#233;rica con los que analizar su posible relaci&#243;n con el desarrollo fetal y la salud del reci&#233;n nacido&#46;</p> <span class="elsevierStyleSectionTitle">Discusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El protocolo que se presenta y el tipo de estudio permiten obtener una aproximaci&#243;n a la exposici&#243;n individual a contaminantes atmosf&#233;ricos&#46; Por &#250;ltimo&#44; el elevado n&#250;mero de participantes &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>4&#46;000&#41;&#44; as&#237; como la heterogeneidad de las caracter&#237;sticas ambientales y sociodemogr&#225;ficas&#44; acrecienta el potencial del estudio&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">The INMA &#40;INfancia y Medio Ambiente &#91;Spanish for Environment and Childhood&#93;&#41; project is a cooperative research network&#46; This project aims to study the effects of environment and diet on fetal and early childhood development&#46; This article aims to present the air pollutant exposure protocol during pregnancy and fetal and early childhood development of the INMA project&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">The information to assess air pollutant exposure during pregnancy is based on outdoor measurement of air pollutants &#40;nitrogen dioxide &#91;NO<span class="elsevierStyleInf">2</span>&#93;&#44; volatile organic compounds &#91;VOC&#93;&#44; ozone&#44; particulate matter &#91;PM<span class="elsevierStyleInf">10</span>&#44; PM<span class="elsevierStyleInf">2&#44;5</span>&#93; and of their composition &#91;polycyclic aromatic hydrocarbons&#93;&#41;&#59; measurement of indoor and personal exposure &#40;VOC and NO<span class="elsevierStyleInf">2</span>&#41;&#59; urinary measurement of a biological marker of hydrocarbon exposure &#40;1-hydroxypyrene&#41;&#59; and data gathered by questionnaires and geographic information systems&#46; These data allow individual air pollutant exposure indexes to be developed&#44; which can then be used to analyze the possible effects of exposure on fetal development and child health&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">This protocol and the type of study allow an approximation to individual air pollutant exposure to be obtained&#46; Finally&#44; the large number of participants &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>4&#44;000&#41;&#44; as well as their geographic and social diversity&#44; increases the study&#39;s potential&#46;</p>"
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