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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Nitrate and trace elements have been associated with diverse health effects&#46; One of the main routes of human exposure is water ingestion&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Some of these elements are naturally ubiquitous and mobile in the environment&#44; but can accumulate in soils and water sources due to the use of fertilizers&#44; industrial emissions and other human activities&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Nitrate is classified as a probable human carcinogen under conditions that result in endogenous formation of N-nitroso compounds&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Arsenic&#44; cadmium&#44; chromium &#40;IV&#41; and some nickel compounds are recognized carcinogens and cause other health effects&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Lead is neurotoxic and selenium and zinc have a likely inverse relationship with gastric&#44; prostate and breast cancer&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Nitrate and many trace elements are regulated in the European Union&#44; Spain&#44; the United States and other countries&#46; Although zinc is not regulated&#44; water containing &#62; 3<span class="elsevierStyleHsp" style=""></span>mg&#47;L of zinc is not acceptable for human intake&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Systematic and published information on levels in Spain is limited and the available data are restricted to specific areas or small study populations&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">We aimed to describe levels of nitrate and trace elements in tap and bottled water in the study areas of the Spanish Multicase-Control study of Cancer &#40;MCC-Spain&#41;&#46; Our ultimate goal was to provide relevant information for expossure assessment to water contaminants in this population&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Methods</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Design and study areas</span><p id="par0020" class="elsevierStylePara elsevierViewall">A descriptive analysis was conducted within the framework of the MCC-Spain study&#44; carried out in 11 Spanish provinces &#40;<a class="elsevierStyleCrossRef" href="#tbl1">table 1</a>&#41;&#44; with 53 urban and 14 rural municipalities &#40;&#60;5000 inhabitants&#41; according to population records in 2010&#46;</p><elsevierMultimedia ident="tbl1"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Water sampling</span><p id="par0025" class="elsevierStylePara elsevierViewall">Tap water samples were collected between March and July 2010 in 227 randomly selected locations &#40;households and public buildings&#41;&#46; The number of samples per area was defined according to the number of person-years included in the MCC study&#46; Sampling procedures followed a common protocol&#46; In January 2011&#44; we purchased a 500<span class="elsevierStyleHsp" style=""></span>mL bottle of the nine most frequently consumed brands in Spain&#44; according to the National Association of Bottled Water Companies<span class="elsevierStyleItalic">&#46;</span></p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Laboratory analysis</span><p id="par0030" class="elsevierStylePara elsevierViewall">Levels of nitrate and seven trace elements &#40;arsenic&#44; nickel&#44; chromium&#44; cadmium&#44; lead&#44; selenium and zinc&#41; were measured at the Public Health Laboratory of Gipuzkoa &#40;Spain&#41;&#44; certified by the National Accreditation Institution&#46; Nitrate was quantified by ultraviolet spectrophotometry with 0&#46;5&#47;1&#46;0<span class="elsevierStyleHsp" style=""></span>mg&#47;L detection&#47;quantification &#40;DL&#47;QL&#41; limits&#46; Arsenic&#44; nickel&#44; chromium&#44; cadmium and lead were measured by graphite furnace atomic absorption spectrophotometry &#40;GF-AAS&#41;&#44; selenium by hydride generation &#40;HG-AAS&#41;&#44; and zinc by flame &#40;F-AAS&#41;&#46; DL&#47;QL are detailed in <a class="elsevierStyleCrossRef" href="#tbl2">table 2</a>&#46;</p><elsevierMultimedia ident="tbl2"></elsevierMultimedia></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Statistical analysis</span><p id="par0035" class="elsevierStylePara elsevierViewall">Differences between study areas were tested with the Kruskall Wallis rank test&#46; Nitrate levels were compared between urban and rural municipalities in provinces where both types of municipality were sampled &#40;Cantabria&#44; Leon and Navarre&#41; by applying the Mann Whitney U test&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Results</span><p id="par0040" class="elsevierStylePara elsevierViewall">Nitrate was quantified in 222 tap water samples &#40;97&#46;8&#37;&#41;&#46; Median levels ranged from 1&#46;4<span class="elsevierStyleHsp" style=""></span>mg&#47;L &#40;Leon&#41; to 10&#46;4<span class="elsevierStyleHsp" style=""></span>mg&#47;L &#40;Barcelona&#41; and differences among study areas were significant &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46; Most determinations in Valencia and Barcelona were in the highest quartile overall &#40;&#62; 7<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#41;&#46; Levels in rural and urban municipalities were similar &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;86&#41;&#46; Nitrate was quantified in eight bottled water samples &#40;88&#46;9&#37;&#41; with a maximum level of 15&#46;6<span class="elsevierStyleHsp" style=""></span>mg&#47;L &#40;<a class="elsevierStyleCrossRef" href="#tbl1">table 1</a>&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">On average&#44; trace elements were below the quantification limit in 94&#37; of tap water samples&#46; Zinc was the most frequently quantified element &#40;32&#46;8&#37;&#41; in all areas except Granada&#46; Arsenic was quantified in Barcelona&#44; Leon and Madrid&#46; Cadmium was quantified in Madrid and selenium in Gipuzkoa&#46; Chromium was found in Gipuzkoa&#44; Leon and Madrid&#46; Lead was quantified in Barcelona&#44; Gipuzkoa&#44; Madrid and Navarre and nickel in Barcelona and Navarre&#46; Differences among areas were significant for arsenic &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;03&#41;&#46; Trace elements were unquantifiable in bottled water samples &#40;<a class="elsevierStyleCrossRef" href="#tbl2">table 2</a>&#41;&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0050" class="elsevierStylePara elsevierViewall">Nitrate and trace elements were below regulatory limits in 227 municipal water samples from 11 Spanish provinces in Spain&#46; Trace elements were under quantification limits in 94&#37; of the samples&#46; Significant differences among areas were observed for nitrate and arsenic&#46; Only nitrate was measurable in bottled water samples&#44; at concentrations below regulatory limits&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">We found similar levels of nitrate in urban and rural areas&#46; Nitrate levels are usually higher in agricultural &#40;rural&#41; areas&#46; However&#44; in urban regions&#44; nitrate could be produced by industrial sources&#44; wastewater and solid waste disposal&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> In addition&#44; water supplying urban areas could be collected in rural regions&#46; Our study had limited power to verify urban-rural differences&#44; because most of the study areas included only urban municipalities&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">We did not find nitrate levels exceeding regulatory limits in tap water&#44; contrary to studies in France<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> and Sicily&#44;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> where 6&#37; of 2019 samples and 4&#46;7&#37; of 667 samples&#44; respectively&#44; exceeded this limit&#46; Our measurements are consistent with Spanish reports from Galicia<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> &#40;0-55&#46;4<span class="elsevierStyleHsp" style=""></span>mg&#47;L in spring water&#41; and Tenerife &#40;mean<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleHsp" style=""></span>mg&#47;L in tap water&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> Our results confirm that nitrate levels differ geographically&#44; which could be explained by several environmental factors such as water source &#40;ground vs&#46; surface&#41;&#44; land use and soil characteristics&#44; among others&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">Arsenic values were below the quantification limit in 96&#46;5&#37; of tap water samples&#44; differing from Spanish reports of levels exceeding the regulatory limits &#40;10<span class="elsevierStyleHsp" style=""></span>&#956;g&#47;L&#41; in Madrid<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a>&#44; Leon<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> and Caldes de Malavella&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> The available literature shows wide variability among regions&#44; due to natural geologic characteristics and anthropogenic sources of contamination&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Even the maximum zinc levels measured in Madrid &#40;&#8776;1&#46;7<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#41; did not exceed the recommended limit to avoid toxic effects &#40;3<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#41; and were similar to results from Finland &#40;1&#46;1<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Higher concentrations of zinc&#44; lead&#44; chromium&#44; nickel&#44; cooper and iron could be observed due to release from piping and fittings&#46; According to a study performed in the Basque country&#44;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a> this contaminant pathway is not important in Spain&#44; which could explain the low levels found of nickel and other trace elements&#46; Selenium was mainly unquantifiable&#44; probably because most of the chemical forms remain fixed to soils and do not reach drinking water&#46; Further research is needed to understand the major environmental determinants of trace element levels in drinking water&#44; given their potential effects&#44; possibly protective&#44; on some cancers&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">Nitrate levels in bottled water were similar to those reported in Tenerife &#40;range 0&#46;4-12<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#41;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> and other European bottled waters &#40;means from &#60;0&#46;04 to 18&#46;1<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#41; analyzed in a Canadian study<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> but were higher than those found in Germany &#40;median 1&#46;08<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> Studies from the United States and Germany<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> found arsenic&#44; cadmium&#44; zinc&#44; selenium and nickel exceeding regulatory levels&#44; but our results&#44; mostly below the regulatory limits&#44; were also verified in other countries&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">We provide broader information than that found in previous Spanish reports on water contaminants&#46; In addition&#44; to our knowledge&#44; this is the first study measuring various trace elements in Spanish bottled water&#46; Since nitrate levels in drinking water were under regulatory limits&#44; specific recommendations about water intake are not warranted&#46; Some implications for exposure assessment are the following&#58; <span class="elsevierStyleItalic">1&#41;</span> geographical variability in nitrate levels should be taken into account&#59; <span class="elsevierStyleItalic">2&#41;</span> drinking water does not appear to be an important source of exposure to trace elements in the study areas&#59; and <span class="elsevierStyleItalic">3&#41;</span> the contribution of bottled water intake to nitrate exposure&#44; so far considered insignificant&#44; needs further analysis&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In conclusion&#44; nitrate levels differ significantly among Spanish regions but are always under the regulatory limits&#46; Trace element levels are low and are mainly unquantifiable in tap and bottled water&#46; This information is helpful to evaluate exposure and the association of these contaminants with prevalent tumors in the Spanish population&#46;<elsevierMultimedia ident="tb0005"></elsevierMultimedia></p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Authors&#8217; contributions</span><p id="par0100" class="elsevierStylePara elsevierViewall">N&#46; Espejo-Herrera performed the statistical analysis and drafted the manuscript under the supervision of C&#46;M&#46; Villanueva&#46; E&#46; Ulibarrena performed the laboratory analysis&#46; All the authors participated in the study design&#44; data collection&#44; review and interpretation of the results&#46; The final manuscript was reviewed and approved by all the authors&#46; All members of the Water Working Group of the MCC-Spain study&#44; listed as co-authors in the Annex&#44; contributed to data collection&#44; water sampling in the study areas and reviewed the results of the study&#46;</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Funding</span><p id="par0105" class="elsevierStylePara elsevierViewall">This study was funded by the Instituto de Salud Carlos III FEDER &#40;PI08&#47;0533&#44; PI08&#47;1770&#44; PI08&#47;1359&#44; PI09&#47;1662&#41;&#44; FIS PI09&#47;00773&#44; Acci&#243;n Transversal del C&#225;ncer del Consejo de Ministros del 11&#47;10&#47;2007 and the CIBER de Epidemiolog&#237;a y Salud P&#250;blica&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Competing interests</span><p id="par0110" class="elsevierStylePara elsevierViewall">None&#46;</p></span></span>"
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            1 => "Drinking water"
            2 => "Tap water"
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            1 => "Agua de consumo"
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            3 => "Agua embotellada"
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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To describe levels of nitrate and trace elements in drinking water from the study areas of a multicase-control study of cancer in Spain &#40;MCC-Spain&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A total of 227 tap water samples were randomly collected from 67 municipalities in 11 provinces and the nine most frequently consumed bottled water brands were sampled to measure levels of nitrate&#44; arsenic&#44; nickel&#44; chromium&#44; cadmium&#44; lead&#44; selenium and zinc&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The median nitrate level was 4&#46;2<span class="elsevierStyleHsp" style=""></span>mg&#47;l &#40;range<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>1-29&#46;0&#41;&#44; with similar levels in rural and urban municipalities &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;86&#41;&#46; Trace elements were unquantifiable in 94&#37; of tap water samples&#46; Differences between areas were significant for nitrate &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; and arsenic &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;03&#41;&#46; Only nitrate was quantifiable in bottled water &#40;range 2&#46;3-15&#46;6<span class="elsevierStyleHsp" style=""></span>mg&#47;l&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Nitrate levels in municipal water differed between regions and were below the regulatory limit in all samples&#44; including bottled water&#46; Trace element levels were low and mainly unquantifiable in tap and bottled water&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Determinar las concentraciones de nitrato y de elementos traza en el agua de consumo de las &#225;reas del estudio Multicaso-Control de C&#225;ncer en Espa&#241;a &#40;MCC-Spain&#41;&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se tomaron al azar 227 muestras de agua municipal en 67 municipios de 11 provincias&#44; y 9 muestras de las aguas embotelladas m&#225;s consumidas&#44; para cuantificar la cantidad presente de nitrato&#44; ars&#233;nico&#44; n&#237;quel&#44; cromo&#44; cadmio&#44; plomo y zinc&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">La mediana de las cifras de nitrato fue 4&#44;2<span class="elsevierStyleHsp" style=""></span>mg&#47;l &#40;rango<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>1-29&#44;0&#41;&#44; con similares resultados en municipios urbanos y rurales &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;86&#41;&#46; Los elementos traza fueron incuantificables en el 94&#37; de las muestras de agua municipal&#46; Se observaron diferencias entre &#225;reas para nitrato &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; y ars&#233;nico &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;03&#41;&#46; Solo el nitrato fue cuantificable en el agua embotellada &#40;rango 2&#44;3-15&#44;6<span class="elsevierStyleHsp" style=""></span>mg&#47;l&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La cantidad de nitrato en el agua municipal difiere entre regiones y es menor que el l&#237;mite regulatorio en todas las muestras&#46; Los elementos traza son mayormente incuantificables tanto en el agua municipal como en la embotellada&#46;</p>"
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            "apendice" => "<p id="par0120" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Co-authors&#58;</span> Gl&#242;ria Carrasco-Turigas&#44; Esther Gr&#224;cia-Laved&#225;n&#44; Ana Espinosa &#40;Center for Research in Environmental Epidemiology&#44; CREAL&#44; Barcelona&#41;&#59; Victor Moreno &#40;Catalan Institute of Oncology&#44; ICO&#44; Barcelona&#59; Biomedical Research Institute&#44; IDIBELL&#59; University of Barcelona&#44; UB&#41;&#59; Laura Costas &#40;Catalan Institute of Oncology&#44; ICO&#44; Barcelona&#41;&#59; Marina Poll&#225;n&#44; Pablo Fern&#225;ndez Navarro&#44; Javier Garc&#237;a&#44; Esther Garc&#237;a-Esquinas &#40;Cancer and Environmental Epidemiology Unit&#44; National Center for Epidemiology&#44; Carlos III Institute of Health&#44; Madrid&#41;&#59; Margarita Palau &#40;National Information System for Drinking Water&#44; SINAC&#41;&#59; Estefan&#237;a Toledo &#40;Public Health Institute of Navarra&#59; Department of Preventive Medicine and Public Health&#44; University of Navarre&#44; Pamplona&#41;&#59; Jone M&#46; Altzibar&#44; Itziar Zaldua &#40;Public Health Division of Gipuzkoa&#41;&#59; Vicente Mart&#237;n &#40;University of Le&#243;n&#41;&#59; Juan Alguacil &#40;Center for Research in Environment and Health&#44; CYSMA&#44; University of Huelva&#41;&#59; and Rosana Peir&#243; &#40;Center for Research in Public Health&#44; CSISP&#44; Valencia&#41;&#44; as members of the MCC-Spain Water Working Group&#46;</p>"
            "titulo" => "Annex"
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          "leyenda" => "<p id="spar0625" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">a</span>Mann-Whitney U test&#46;<span class="elsevierStyleSup">b</span>According to Spanish legislation &#40;Royal Decree 140&#47;2003&#41;&#44; European Legislation &#40;Directive 98&#47;83&#47;CE&#41; and the World Health Organization &#40;WHO Guidelines 2011&#41;&#44; US Environmental Protection Agency &#40;US Federal Register 40CFR&#46; July 1991&#41; equivalent to 10<span class="elsevierStyleHsp" style=""></span>mg&#47;l of nitrate- N&#46;<span class="elsevierStyleSup">c</span>According to Spanish legislation &#40;Royal Decree 1074&#47;2002&#41;&#46;</p>"
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                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="3" align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Number of samples</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="5" align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Levels &#40;mg&#47;L&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="6" align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Levels &#40;mg&#47;L&#41; by urban-rural municipalities</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">&#62;Quantification limit &#40;1 mg&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">&#37; &#62;4th percentile &#40;7 mg&#47;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Min&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">25th percentile&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Median&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">75th percentile&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Max&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">UrbanGeometric Mean&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">95&#37;CI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">N&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">RuralGeometric Mean&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">95&#37;CI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">N&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p value</span><span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Asturias&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">23&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;2-4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Barcelona&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">51&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">60&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;7-10&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cantabria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">20&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;4- 7&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;4-10&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">0&#46;29</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Gipuzkoa&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t  " colspan="12" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Regulatory limits</span><span class="elsevierStyleSup">b</span><span class="elsevierStyleItalic">&#58; 50 mg&#47;l &#40;Spain&#44; EU&#44; WHO&#41;&#59; 44 mg&#47;L &#40;USA</span>&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="16" align="left" valign="\n
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                  \t\t\t\t">Bottled water</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Range&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N&#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N&#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Range&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1&#46;0-1&#46;0<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1&#46;0-1&#46;2&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">61-527<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">24<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">3 &#40;12&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1 &#40;4&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">8 &#40;33&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Granada</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Range&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Range&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">2&#40;12&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1 &#40;6&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">8 &#40;50&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Range&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>N &#40;&#37;&#41; &#62;QL<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">69 &#40;32&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
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