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        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Las enfermedades mentales presentan una baja mortalidad pero son altamente discapacitantes&#44; lo que ha hecho que su diagn&#243;stico y tratamiento ocupen un papel cada vez m&#225;s relevante en la terapia actual y en las pol&#237;ticas sanitarias&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">En este escenario se plante&#243; este estudio&#44; que pretende analizar los factores que pueden haber influido en la utilizaci&#243;n de antidepresivos y antipsic&#243;ticos en Espa&#241;a durante el per&#237;odo 1997-2004&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Los antidepresivos tric&#237;clicos son los f&#225;rmacos de referencia para tratar la depresi&#243;n&#44; pero a su perfil de efectos adversos se ha atribuido una falta de adherencia&#46; La b&#250;squeda de una mejor tolerancia&#44; en un mercado en auge&#44; ha favorecido la s&#237;ntesis de nuevos antidepresivos y la investigaci&#243;n de nuevas indicaciones&#46; Esto explicar&#237;a en buena parte el crecimiento del consumo de este grupo&#44; tanto en unidades como en ventas&#44; que ha pasado de 14&#44;14 a 26&#44;79 millones de envases y de 168&#44;61 a 447&#44;11 millones de euros en valor&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">En el caso de los antipsic&#243;ticos su utilizaci&#243;n se ha mantenido m&#225;s o menos estable&#44; pasando de 11&#44;74 a 12&#44;65 millones de envases&#44; pero el aumento de facturaci&#243;n ha sido espectacular&#58; ha pasado de 61&#44;84 a 317&#44;46 millones de euros&#59; la risperidona y la olanzapina son las principales causantes de este incremento&#46; Muchos pacientes tratados con antipsic&#243;ticos de primera generaci&#243;n han pasado a ser tratados con estos nuevos antipsic&#243;ticos&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Algunos factores que han contribuido a la situaci&#243;n actual son el mayor n&#250;mero de depresiones diagnosticadas&#44; as&#237; como de otras enfermedades mentales&#44; el aumento del n&#250;mero de indicaciones aprobadas y el crecimiento de la poblaci&#243;n anciana tratada con los nuevos antipsic&#243;ticos&#46; Todo ello&#44; junto con el marketing promocional&#44; ha disparado la utilizaci&#243;n de los principios activos de m&#225;s reciente comercializaci&#243;n&#46;</p>"
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Parte III. Recursos asistenciales y utilización
Luces y sombras de la prestación farmacéutica en España: a propósito de los antidepresivos y antipsicóticos
Positive and negative aspects of pharmaceutical services in Spain: about antidepressants and antipsychotics
Lourdes Girona-Brumósa,
Autor para correspondencia
lgirona@vhebron.net

Correspondencia: Lourdes Girona-Brumós. Área de Traumatología y Rehabilitación. Servicio de Farmacia. Hospital Universitario Vall d’Hebron. Paseo del Valle de Hebron, 119-129. 08035 Barcelona. España.
, Ramón Ribera-Montañáb, Juan Carlos Juárez-Giméneza, María Pilar Lalueza-Brotoa
a Servicio de Farmacia. Área de Traumatología y Rehabilitación. Hospital Universitario Vall d’Hebron. Barcelona. España
b Servicio de Farmacia. Centros Asistenciales Dr. Emili Mira i López. Santa Coloma de Gramenet. Barcelona. España
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        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Las enfermedades mentales presentan una baja mortalidad pero son altamente discapacitantes&#44; lo que ha hecho que su diagn&#243;stico y tratamiento ocupen un papel cada vez m&#225;s relevante en la terapia actual y en las pol&#237;ticas sanitarias&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">En este escenario se plante&#243; este estudio&#44; que pretende analizar los factores que pueden haber influido en la utilizaci&#243;n de antidepresivos y antipsic&#243;ticos en Espa&#241;a durante el per&#237;odo 1997-2004&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Los antidepresivos tric&#237;clicos son los f&#225;rmacos de referencia para tratar la depresi&#243;n&#44; pero a su perfil de efectos adversos se ha atribuido una falta de adherencia&#46; La b&#250;squeda de una mejor tolerancia&#44; en un mercado en auge&#44; ha favorecido la s&#237;ntesis de nuevos antidepresivos y la investigaci&#243;n de nuevas indicaciones&#46; Esto explicar&#237;a en buena parte el crecimiento del consumo de este grupo&#44; tanto en unidades como en ventas&#44; que ha pasado de 14&#44;14 a 26&#44;79 millones de envases y de 168&#44;61 a 447&#44;11 millones de euros en valor&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">En el caso de los antipsic&#243;ticos su utilizaci&#243;n se ha mantenido m&#225;s o menos estable&#44; pasando de 11&#44;74 a 12&#44;65 millones de envases&#44; pero el aumento de facturaci&#243;n ha sido espectacular&#58; ha pasado de 61&#44;84 a 317&#44;46 millones de euros&#59; la risperidona y la olanzapina son las principales causantes de este incremento&#46; Muchos pacientes tratados con antipsic&#243;ticos de primera generaci&#243;n han pasado a ser tratados con estos nuevos antipsic&#243;ticos&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Algunos factores que han contribuido a la situaci&#243;n actual son el mayor n&#250;mero de depresiones diagnosticadas&#44; as&#237; como de otras enfermedades mentales&#44; el aumento del n&#250;mero de indicaciones aprobadas y el crecimiento de la poblaci&#243;n anciana tratada con los nuevos antipsic&#243;ticos&#46; Todo ello&#44; junto con el marketing promocional&#44; ha disparado la utilizaci&#243;n de los principios activos de m&#225;s reciente comercializaci&#243;n&#46;</p>"
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        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Mental disorders mortality rates are low but they are extremely disabling so that the diagnosis and treatment of mental illness is an important task for public health and it is central in current therapy strategies and sanitary policy&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">The aim of this study is to analyse conditions influencing antidepressants and antipsychotics use in Spain from 1997 to 2004&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Tryciclic antidepressants have been of first-choice in depression treatment for many years but their side effects profile are related to a lack of treatment adherence&#46; Trying to increase tolerance&#44; new antidepressants have been developed and research into new therapeutic uses is being done&#46; These are some of the reasons causing an increase in medical utilization and costs&#46; Medical boxes sold have increased from 14&#44;14 million in 1997 to 26&#44;76 million in 2004&#44; meaning 168&#44;61 and 447&#44;11 million euros respectively&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Antipsychotic use has been maintained&#44; 11&#44;74 million boxes in 1997 and 12&#44;65 in 2004&#59; however&#44; there has been a rise in price from 61&#44;84 to 317&#44;46 million euros due to second generation antipsychotics prescription &#40;mainly risperidone and olanzapine&#41;</p><p class="elsevierStyleSimplePara elsevierViewall">Some conditions have contributed to current situation&#58; increased number of diagnosed patients with depression and other mental disorders&#44; new approved therapeutic uses and a rise in elderly people receiving new antipsychotic agents&#46; Moreover&#44; promotional marketing is causing an increase in new recently commercialised drugs use&#46;</p>"
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ISSN: 02139111
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