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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluar el consumo de paracetamol&#44; metamizol y &#225;cido acetilsalic&#237;lico &#40;AAS&#41; en un estudio multic&#233;ntrico&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Pacientes y m&#233;todo&#58; Se analizaron los controles de un estudio de casos y controles hospitalarios &#40;n &#61; 1&#46;029&#41; sobre c&#225;ncer vesical mediante la aplicaci&#243;n de una matriz de medicamentos y principios activos&#46; El motivo de ingreso de los controles no se asociaba con el uso cr&#243;nico de analg&#233;sicos&#46; Se utiliz&#243; un modelo de regresi&#243;n log&#237;stica&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El uso cr&#243;nico de AAS fue del 8&#37;&#44; el de paracetamol&#44; del 5&#37; y el de metamizol&#44; del 2&#37;&#46; El AAS fue m&#225;s usado por personas con educaci&#243;n secundaria o superior &#40;<span class="elsevierStyleItalic">odds ratio</span> &#91;OR&#93;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#44;0&#44; intervalo de confianza &#91;IC&#93; del 95&#37;&#44; 1&#44;52-2&#44;93&#41;&#46; Las mujeres usaron m&#225;s paracetamol &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#44;91&#59; IC del 95&#37;&#44; 1&#44;30-2&#44;80&#41; y metamizol &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#44;80&#59; IC del 95&#37;&#44; 1&#44;49-4&#44;47&#41;&#46; Los menores de 65 a&#241;os usaron m&#225;s metamizol&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El uso cr&#243;nico de AAS y paracetamol es bajo comparado con el de Estados Unidos o el norte de Europa&#44; aunque es parecido al del sur de Europa&#46; Hay diferencias en el uso de analg&#233;sicos en funci&#243;n de las variables sociodemogr&#225;ficas&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To evaluate the use of acetaminophen &#40;paracetamol&#41;&#44; aspirin and dipyrone &#40;metamizol&#41; in a multicenter study&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">We analyzed the controls of a hospitalbased case-control study &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1029&#41; of bladder cancer using a matrix of drugs and active principles&#46; The admission diagnosis of the study controls was not associated with chronic analgesic use&#46; A logistic regression model was used&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Eight percent of the controls were regular users of aspirin&#44; 5&#37; regularly used acetaminophen and 2&#37; regularly used dipyrone&#46; Aspirin was more frequently used by subjects with at least secondary education &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#46;0&#59; 95&#37; CI&#44; 1&#46;52-2&#46;93&#41;&#46; Women more frequently used acetaminophen &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;91&#59; 95&#37; CI&#44; 1&#46;30-2&#46;80&#41; and dipyrone &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#46;80&#59; 95&#37; CI&#44; 1&#46;49-4&#46;47&#41;&#46; Subjects under 65 years old more frequently used dipyrone&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">Chronic use of aspirin and acetaminophen is lower than that reported in North America or northern Europe and is similar to that seen in southern Europe&#46; Differences in the pattern of analgesic use were found among sociodemographic population groups&#46;</p>"
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Originales breves
Uso de analgésicos y ácido acetilsalicílico en un estudio multicéntrico en España
Use of analgesics and aspirin in a Spanish multicenter study
Joan Fortunya,
Autor para correspondencia
jfortuny@imim.es

Correspondencia: Dr. Joan Fortuny Moya. Unitat de Recerca Respiratòria i Ambiental. Institut Municipal d’Investigació Mèdica (IMIM). Doctor Aiguader, 80. 08003 Barcelona. España.
, Debra Silvermanb, Núria Malatsa, Adonina Tardónc, Reina García-Closasd, Consol Serrae, Alfredo Carratof, Nat Rothmanb, Mustafa Dosemecib, Manolis Kogevinasa
a Institut Municipal d’Investigació Mèdica (IMIM), Barcelona, España
b Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD, Estados Unidos
c Instituto Universitario de Oncología. Universidad de Oviedo, Oviedo, Asturias, España
d Hospital Universitario de Canarias, La Laguna, Tenerife, España
e Consorci Hospitalari Parc Taulí, Sabadell y Universitat Pompeu Fabra, Barcelona, España
f Hospital General d’Elx, Elx, Alicante, España
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluar el consumo de paracetamol&#44; metamizol y &#225;cido acetilsalic&#237;lico &#40;AAS&#41; en un estudio multic&#233;ntrico&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Pacientes y m&#233;todo&#58; Se analizaron los controles de un estudio de casos y controles hospitalarios &#40;n &#61; 1&#46;029&#41; sobre c&#225;ncer vesical mediante la aplicaci&#243;n de una matriz de medicamentos y principios activos&#46; El motivo de ingreso de los controles no se asociaba con el uso cr&#243;nico de analg&#233;sicos&#46; Se utiliz&#243; un modelo de regresi&#243;n log&#237;stica&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El uso cr&#243;nico de AAS fue del 8&#37;&#44; el de paracetamol&#44; del 5&#37; y el de metamizol&#44; del 2&#37;&#46; El AAS fue m&#225;s usado por personas con educaci&#243;n secundaria o superior &#40;<span class="elsevierStyleItalic">odds ratio</span> &#91;OR&#93;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#44;0&#44; intervalo de confianza &#91;IC&#93; del 95&#37;&#44; 1&#44;52-2&#44;93&#41;&#46; Las mujeres usaron m&#225;s paracetamol &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#44;91&#59; IC del 95&#37;&#44; 1&#44;30-2&#44;80&#41; y metamizol &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#44;80&#59; IC del 95&#37;&#44; 1&#44;49-4&#44;47&#41;&#46; Los menores de 65 a&#241;os usaron m&#225;s metamizol&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El uso cr&#243;nico de AAS y paracetamol es bajo comparado con el de Estados Unidos o el norte de Europa&#44; aunque es parecido al del sur de Europa&#46; Hay diferencias en el uso de analg&#233;sicos en funci&#243;n de las variables sociodemogr&#225;ficas&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To evaluate the use of acetaminophen &#40;paracetamol&#41;&#44; aspirin and dipyrone &#40;metamizol&#41; in a multicenter study&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">We analyzed the controls of a hospitalbased case-control study &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1029&#41; of bladder cancer using a matrix of drugs and active principles&#46; The admission diagnosis of the study controls was not associated with chronic analgesic use&#46; A logistic regression model was used&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Eight percent of the controls were regular users of aspirin&#44; 5&#37; regularly used acetaminophen and 2&#37; regularly used dipyrone&#46; Aspirin was more frequently used by subjects with at least secondary education &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#46;0&#59; 95&#37; CI&#44; 1&#46;52-2&#46;93&#41;&#46; Women more frequently used acetaminophen &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;91&#59; 95&#37; CI&#44; 1&#46;30-2&#46;80&#41; and dipyrone &#40;OR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#46;80&#59; 95&#37; CI&#44; 1&#46;49-4&#46;47&#41;&#46; Subjects under 65 years old more frequently used dipyrone&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">Chronic use of aspirin and acetaminophen is lower than that reported in North America or northern Europe and is similar to that seen in southern Europe&#46; Differences in the pattern of analgesic use were found among sociodemographic population groups&#46;</p>"
      ]
    ]
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              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
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                0 => array:1 [
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            1 => array:3 [
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ISSN: 02139111
Idioma original: Español
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