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"titulo" => "Descriptive epidemiology of non-meningococcal bacterial meningitis in the province of Saragossa [Spain] from 1999 to 2004. Evaluation of the Epidemiological Surveillance System"
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"resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Describir las meningitis no meningocócicas bacterianas (MnMB) y evaluar el Sistema de Vigilancia Epidemiológica (SVE) en la provincia de Zaragoza entre 1999 y 2004.</p> <span class="elsevierStyleSectionTitle">Métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se utilizó el registro de enfermedades de declaración obligatoria (EDO) y el conjunto mínimo básico de datos (CMBD). Se evaluó el SVE utilizando criterios de los Centers for Disease Control and Prevention, estimando la exhaustividad mediante captura-recaptura.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se notificaron 111 casos de MnMB (62,2% en hombres). La edad media fue de 40,7 años. La mayor proporción de casos (16,5%) fue en niños menores de 2 años. La forma clínica en el 81,1% de los casos fue la meningitis; el 70,3% fue diagnosticada por cultivo. Aparecieron <span class="elsevierStyleItalic">Streptococcus</span> en el 54% de los casos (el 82% por <span class="elsevierStyleItalic">S. pneumoniae</span>)<span class="elsevierStyleItalic">,</span> enterobacterias en el 5,4%, <span class="elsevierStyleItalic">Lysteria</span> y <span class="elsevierStyleItalic">Staphylococcus</span> en el 4,5%, <span class="elsevierStyleItalic">Pseudomona aeruginosa</span> en el 1,8%, y <span class="elsevierStyleItalic">Haemophilus influenzae</span> en el 0,9%. La incidencia por 100.000 habitantes fue entre 1,6 en 2004 y 2,6 en 2001. La letalidad fue del 7,3%. La exhaustividad del sistema EDO fue máxima en el año 2001 (del 84,4%). La exhaustividad conjunta con CMBD fue superior al 85% y la oportunidad fue de 2 días. La aceptabilidad del sistema fue buena, ya que el 75% de las variables estaban cumplimentadas en el 97% de las encuestas.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Se destaca la relevancia de la evaluación del SVE en función de sus resultados. Las MnMB debidas a <span class="elsevierStyleItalic">S. pneumoniae</span> representan un grupo significativo y su letalidad es elevada. La exhaustividad del SVE en Zaragoza supera el 80%, al considerar EDO y CMBD. La incorporación del CMBD en la vigilancia facilitaría una aproximación a la incidencia real de algunas EDO.</p>"
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"en" => array:2 [
"titulo" => "Abstract"
"resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p class="elsevierStyleSimplePara elsevierViewall">To describe non-meningococcal bacterial meningitis (nMM) and to evaluate the Epidemiological Surveillance System (ESS) in the province of Saragossa (Spain) between 1999 and 2004.</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">Information was obtained from the register of diseases subject to mandatory reporting and the Minimum Basic Data Set (MBDS). The ESS was evaluated by using the Centers for Disease Control and Prevention (CDC) criteria and by estimating the completeness of the system through the capture-recaptu re technique.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">111 cases of nMM were notified (62.2% in males) and the mean age was 40.7 years. The largest proportion of cases (16.5%) occurred in children under 2 years of age. The clinical presentation was meningitis in 81.1%. Diagnosis was through bacterial culture in 70.3%. <span class="elsevierStyleItalic">Streptococcus</span> sp. was found in 54% (82% due to <span class="elsevierStyleItalic">S. pneumoniae</span>)<span class="elsevierStyleItalic">,</span> enterobacteria in 5.4%, <span class="elsevierStyleItalic">Listeria</span> and <span class="elsevierStyleItalic">Staphylococcus</span> in 4.5%, <span class="elsevierStyleItalic">Pseudomonas</span><span class="elsevierStyleItalic">aeruginosa</span> in 1.8%, and <span class="elsevierStyleItalic">Haemophilus</span><span class="elsevierStyleItalic">influenzae</span> in 0.9%. The incidence rate per 100,000 inhabitants was 1.6 in 2004 and 2.6 in 2001. The case fatality was 7.3%. The completeness of the mandatory reporting system reached a peak in 2004 at 84.4%. The combined completeness of the MBDS and the mandatory reporting system was above 85% and timeliness of reporting was 2 days. The acceptability of the system was high since 75% of all variables were complete in 97% of the questionnaires.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">We</span> highlight the importance of evaluation of the ESS, based on its results. nMM due to <span class="elsevierStyleItalic">S. pneumoniae</span> represent an important group of diseases and their case fatality is high. The completeness of the ESS in Saragossa was over 80% when the mandatory reporting system and the MBDS were combined. Incorporating the MBDS into surveillance would facilitate the estimation of the real incidence of various diseases subject to mandatory reporting.</p>"
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