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"resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La enfermedad neumocócica es una causa frecuente de morbilidad y mortalidad entre la población infantil. La reciente autorización de la vacuna conjugada heptavalente ha incrementado el interés científico que suscita esta enfermedad. El objetivo de este estudio es conocer las características epidemiológicas y clínicas, así como la evolución de esta enfermedad invasiva en la población infantil de la Comunidad Valenciana.</p> <span class="elsevierStyleSectionTitle">Método</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Los datos se han obtenido de las historias clínicas de los niños menores de 15 años, con aislamiento del neumococo, atendidos en todos los hospitales públicos de la Comunidad Valenciana durante el período 1996-2000. La evolución de la incidencia se valoró mediante la comparación de tasas, los signos clínicos y su evolución (secuelas y letalidad) mediante la evaluación de la frecuencia y su distribución por edades.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se registró un total de 127 casos, lo que representa un promedio de tasa anual de 3,89/105 habitantes en los menores de 15 años y de 20,14 en los menores de 2 años. Presentaron antecedentes de problemas de salud un 29,1% de los pacientes. Las manifestaciones clínicas predominantes fueron sepsis/bacteriemia (38%), neumonía (31%) y meningitis (24%). Al alta, presentaban secuelas 10 niños, de los que el 75% eran menores de 2 años. Fallecieron 8 niños (letalidad del 6,3%).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">En nuestro medio, durante el período estudiado, la infección neumocócica se presenta sobre todo en los niños menores de 2 años, así como en los mayores de esta edad con antecedentes de problemas de salud. En estos últimos se ha encontrado una mayor mortalidad. Sería conveniente introducir la enfermedad neumocócica en el Sistema de Vigilancia Epidemiológica, lo que nos permitiría disponer de estimaciones más precisas de su evolución epidemiológica y valorar si la vacuna conjugada es la solución a los problemas que plantea esta bacteria en la actualidad.</p>"
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"resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Pneumococcal disease is an important cause of morbidity and mortality in children. The recent authorization of the heptavalent conjugate vaccine has increased interest in this disease. The objective of this study was to identify the epidemiological and clinical characteristics of this disease, as well as its outcome in the pediatric population of the Autonomous Community of Valencia.</p> <span class="elsevierStyleSectionTitle">Method</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Data were obtained from the medical records of children aged less than 15 years who were positive for pneumococcus isolation on admission to hospital between 1996 and 2000. All the public hospitals of the Autonomous Community of Valencia were included. Changes in incidence were evaluated by comparing rates and outcomes (sequelae and lethality) through frequency and age distribution.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">One hundred twenty-seven cases were registered, giving a mean annual rate of 3.89/105 inhabitants aged less than 15 years. The rate was 20.14 in children aged less than 2 years. A total of 29.1% of the children had previous health problems. The main clinical manifestations included sepsis/ bacteremia (38%), pneumonia (31%) and meningitis (24%). At discharge sequelae were present in 10 children, 75% of whom were aged less than 2 years. Eight children died (6.3% lethality).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">In the period and region studied, pneumococcal infection was present mainly in children aged less than 2 years and in those with previous health problems. In the last few years, mortality has increased. Thus, inclusion of pneumococcal disease in the epidemiological surveillance system would be appropriate to achieve more precise estimations of its epidemiological patterns and to determine whether the conjugate vaccine represents a solution to the problems currently associated with this bacteria.</p>"
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"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Pneumococal vaccine"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:3 [
0 => "D.S. Fedson"
1 => "D.M. Musher"
2 => "J. Eskola"
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]
]
]
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"host" => array:1 [
0 => array:1 [
"LibroEditado" => array:5 [
"titulo" => "Vaccines"
"paginaInicial" => "553"
"paginaFinal" => "607"
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"serieFecha" => "1999"
]
]
]
]
]
]
1 => array:3 [
"identificador" => "bib0010"
"etiqueta" => "2."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:1 [
"autores" => array:1 [
0 => array:2 [
"colaboracion" => "Comité Asesor de Vacunas (CAV) de la Asociación Española de Pediatría (AEP)"
"etal" => false
]
]
]
]
"host" => array:1 [
0 => array:1 [
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"titulo" => "Manual de vacunas en pediatría"
"edicion" => "2a"
"serieFecha" => "2001"
]
]
]
]
]
]
2 => array:3 [
"identificador" => "bib0015"
"etiqueta" => "3."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:1 [
"titulo" => "Neumonías en España"
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:5 [
"tituloSerie" => "Boletín Epidemiológico Microbiológico"
"fecha" => "1997"
"volumen" => "4"
"paginaInicial" => "29"
"paginaFinal" => "36"
]
]
]
]
]
]
3 => array:3 [
"identificador" => "bib0020"
"etiqueta" => "4."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Recommendations of the Advisory Committee on Immunization Practices (ACIP): Prevention of pneumococcal disease"
"autores" => array:1 [
0 => array:2 [
"colaboracion" => "Centers for Disease Control and Prevention (CDC)"
"etal" => false
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0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "MMWR"
"fecha" => "1997"
"volumen" => "46"
"paginaInicial" => "1"
"paginaFinal" => "24"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/9427216"
"web" => "Medline"
]
]
]
]
]
]
]
]
4 => array:3 [
"identificador" => "bib0025"
"etiqueta" => "5."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Situación de la enfermedad invasora por <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> en España"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:1 [
0 => "J. Casal"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"LibroEditado" => array:4 [
"titulo" => "Primer Congreso de la Asociación Española de Vacunología"
"paginaInicial" => "67"
"paginaFinal" => "74"
"serieFecha" => "2001"
]
]
]
]
]
]
5 => array:3 [
"identificador" => "bib0030"
"etiqueta" => "6."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Prevalencia de meningitis neumocócica en niños españoles"
"autores" => array:1 [
0 => array:3 [
"colaboracion" => "Grupo para el Estudio de la Meningitis Neumocócica"
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"autores" => array:5 [
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2 => "C. Rodrigo"
3 => "J.M. Martinón"
4 => "C. Fernández"
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]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "An Esp Pediatr"
"fecha" => "2002"
"volumen" => "56"
"paginaInicial" => "5"
"paginaFinal" => "9"
"link" => array:1 [
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]
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]
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"titulo" => "Epidemiology of invasive pneumococcal disease in infants in Catalonia (Spain) [abstract]. 19th Annual Meeting of the European Society for Pediatric Infectious Disease (ESPID)"
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"autores" => array:6 [
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5 => "N. Cardeñosa"
]
]
]
]
]
"host" => array:1 [
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]
]
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"referencia" => array:1 [
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"autores" => array:1 [
0 => array:2 [
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"autores" => array:6 [
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3 => "I.H. Chang"
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5 => "B. Fireman"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Pediatr Infect Dis J"
"fecha" => "1999"
"volumen" => "18"
"paginaInicial" => "757"
"paginaFinal" => "763"
"link" => array:1 [
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"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10493334"
"web" => "Medline"
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"identificador" => "bib0045"
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"referencia" => array:1 [
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"titulo" => "Pneumococcal conjugate vaccines"
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"autores" => array:2 [
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"Revista" => array:4 [
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"autores" => array:1 [
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"tituloSerie" => "Med Clin (Barc)"
"fecha" => "1998"
"volumen" => "110"
"numero" => "Supl 1"
"paginaInicial" => "44"
"paginaFinal" => "51"
]
]
]
]
]
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"titulo" => "<span class="elsevierStyleItalic">Streptococcus pneumoniae</span> in children in Spain: 1990-1999"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:6 [
0 => "A. Fenoll"
1 => "I. Jado"
2 => "D. Vicioso"
3 => "S. Berrón"
4 => "J.E. Yuste"
5 => "J. Casal"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Acta Paediatrica"
"fecha" => "2000"
"volumen" => "435"
"numero" => "Supl"
"paginaInicial" => "44"
"paginaFinal" => "50"
]
]
]
]
]
]
11 => array:3 [
"identificador" => "bib0060"
"etiqueta" => "12."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Epidemiología de los serotipos y patrones de resistencia del <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> en la Comunidad Valenciana. XIX Reunión Científica de la Sociedad Española de Epidemiología. Murcia, 17-19 octubre de 2001"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "M. Montaner"
1 => "S. Cuellar"
2 => "L.A. Calvo"
3 => "R. Moreno"
4 => "C. Belles"
5 => "M. Gil"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:3 [
"tituloSerie" => "Gac Sanit"
"fecha" => "2001"
"numero" => "Supl 2"
]
]
]
]
]
]
12 => array:3 [
"identificador" => "bib0065"
"etiqueta" => "13."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Variation in penicillin resistance in <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> selected sites, United States"
"autores" => array:1 [
0 => array:2 [
"colaboracion" => "Centers for Disease Control and Prevention (CDC)"
"etal" => false
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "MMWR"
"fecha" => "1999"
"volumen" => "48"
"paginaInicial" => "656"
"paginaFinal" => "661"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10488781"
"web" => "Medline"
]
]
]
]
]
]
]
]
13 => array:3 [
"identificador" => "bib0070"
"etiqueta" => "14."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:1 [
"titulo" => "Vacuna contra el neumococo. Guía práctica para profesionales sanitarios. Monografía Sanitaria. No. 34"
]
]
"host" => array:1 [
0 => array:1 [
"Libro" => array:3 [
"fecha" => "2001"
"editorial" => "Generalitat Valenciana. Conselleria de Sanitat"
"editorialLocalizacion" => "Valencia"
]
]
]
]
]
]
14 => array:3 [
"identificador" => "bib0075"
"etiqueta" => "15."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Preventing pneumococcal disease among infants and young children. Recommendation of the Advisory Committee on Immunization practices (ACIP)"
"autores" => array:1 [
0 => array:2 [
"colaboracion" => "Centers for Disease Control and Prevention (CDC)"
"etal" => false
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "MMWR"
"fecha" => "2000"
"volumen" => "49"
"paginaInicial" => "1"
"paginaFinal" => "35"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/15580784"
"web" => "Medline"
]
]
]
]
]
]
]
]
15 => array:3 [
"identificador" => "bib0080"
"etiqueta" => "16."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Efficacy, safety and immunogenecity of heptavalent pneumococcal conjugate vaccine in children"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "S. Black"
1 => "H. Sinefield"
2 => "B. Fireman"
3 => "F. Lewis"
4 => "P. Ray"
5 => "J.R. Hansen"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Pediatr Infect Dis J"
"fecha" => "2000"
"volumen" => "19"
"paginaInicial" => "187"
"paginaFinal" => "195"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10749457"
"web" => "Medline"
]
]
]
]
]
]
]
]
16 => array:3 [
"identificador" => "bib0085"
"etiqueta" => "17."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Postlicensure evaluation of the effectiveness of seven valent pneumococcal conjugate vaccine"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:6 [
0 => "S. Black"
1 => "H. Sinefield"
2 => "J. Hansen"
3 => "L. Elvin"
4 => "D. Laufer"
5 => "F. Malinoski"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Pediatr Infect Dis J"
"fecha" => "2001"
"volumen" => "20"
"paginaInicial" => "1105"
"paginaFinal" => "1107"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/11740313"
"web" => "Medline"
]
]
]
]
]
]
]
]
17 => array:3 [
"identificador" => "bib0090"
"etiqueta" => "18."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Policy statement: recommendations for the prevention of pneumococcal infections, including the use o pneumococcal conjugate vaccine (Prevnar), pneumococcal polysaccharide vaccine, and antibiotic prophylaxis"
"autores" => array:1 [
0 => array:2 [
"colaboracion" => "Committee of Infections Disease"
"etal" => false
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Pediatrics"
"fecha" => "2000"
"volumen" => "106"
"paginaInicial" => "362"
"paginaFinal" => "366"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10920169"
"web" => "Medline"
]
]
]
]
]
]
]
]
18 => array:3 [
"identificador" => "bib0095"
"etiqueta" => "19."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "<span class="elsevierStyleItalic">Streptococcus pneumoniae</span>"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:1 [
0 => "D.M. Musher"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"LibroEditado" => array:4 [
"titulo" => "Principles and practice of infectious disease"
"paginaInicial" => "2134"
"edicion" => "5th"
"serieFecha" => "2000"
]
]
]
]
]
]
19 => array:3 [
"identificador" => "bib0100"
"etiqueta" => "20."
"referencia" => array:1 [
0 => array:1 [
"host" => array:1 [
0 => array:1 [
"LibroEditado" => array:3 [
"titulo" => "Evolución de la enfermedad invasora bacteriana por <span class="elsevierStyleItalic">Neisseria meningitidis, Haemophilus influenzae</span> y <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> en la población infantil de la Comunidad Valenciana (1996-2000)"
"edicion" => "1a"
"serieFecha" => "2002"
]
]
]
]
]
]
20 => array:3 [
"identificador" => "bib0105"
"etiqueta" => "21."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Meningitis neumocócica en la infancia. Revisión de 28 casos"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:5 [
0 => "S. Mencía"
1 => "J. Casado"
2 => "C. Marín"
3 => "M. González"
4 => "M.J. Ruiz"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "An Esp Pediatr"
"fecha" => "2000"
"volumen" => "53"
"paginaInicial" => "94"
"paginaFinal" => "99"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/11083949"
"web" => "Medline"
]
]
]
]
]
]
]
]
21 => array:3 [
"identificador" => "bib0110"
"etiqueta" => "22."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Meningitis neumocócicas"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:5 [
0 => "F. Asensi"
1 => "M.C. Otero"
2 => "D. Pérez"
3 => "P. Gregori"
4 => "A. Ortí"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:5 [
"tituloSerie" => "An Esp Pediatr"
"fecha" => "2001"
"volumen" => "54"
"paginaInicial" => "188"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/11181218"
"web" => "Medline"
]
]
]
]
]
]
]
]
22 => array:3 [
"identificador" => "bib0115"
"etiqueta" => "23."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Meningitis neumocócica: características epidemiológicas, clínicas y bacteriológicas"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:7 [
0 => "J.A. Soult"
1 => "C. Rangel"
2 => "M. Muñoz"
3 => "J.S. Parrilla"
4 => "F. Díaz"
5 => "J.D. López"
6 => "A. Tovaruela"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "An Esp Pediatr"
"fecha" => "2001"
"volumen" => "55"
"paginaInicial" => "315"
"paginaFinal" => "320"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/11578538"
"web" => "Medline"
]
]
]
]
]
]
]
]
23 => array:3 [
"identificador" => "bib0120"
"etiqueta" => "24."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Worldwide Haemophilus influenzae type b disease at the beginning of the 21st century: global analysis of the disease burden 25 years after the use of the polysaccharide vaccine and a decade after the advent of conjugates"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:1 [
0 => "H. Peltola"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Clin Microbiol Rev"
"fecha" => "2000"
"volumen" => "13"
"paginaInicial" => "302"
"paginaFinal" => "317"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/10756001"
"web" => "Medline"
]
]
]
]
]
]
]
]
24 => array:3 [
"identificador" => "bib0125"
"etiqueta" => "25."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Efficacy of meningococcal serogroup C conjugate vaccine in teenagers and toddlers in England"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:4 [
0 => "M.E. Ramsay"
1 => "N. Andrews"
2 => "E.B. Kaczmarski"
3 => "E. Miller"
]
]
]
]
]
"host" => array:1 [
0 => array:2 [
"doi" => "10.1016/S0140-6736(00)03594-7"
"Revista" => array:6 [
"tituloSerie" => "Lancet"
"fecha" => "2001"
"volumen" => "357"
"paginaInicial" => "195"
"paginaFinal" => "196"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/11213098"
"web" => "Medline"
]
]
]
]
]
]
]
]
25 => array:3 [
"identificador" => "bib0130"
"etiqueta" => "26."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Enfermedad neumocócica invasiva en niños de la Región de Murcia"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:6 [
0 => "M.I. Espín"
1 => "A. Sandoval"
2 => "J. Ruiz"
3 => "J.A. Navarro"
4 => "J. García"
5 => "D. Pérez"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Gac Sanit"
"fecha" => "2002"
"volumen" => "16"
"paginaInicial" => "385"
"paginaFinal" => "391"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/12372183"
"web" => "Medline"
]
]
]
]
]
]
]
]
26 => array:3 [
"identificador" => "bib0135"
"etiqueta" => "27."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:1 [
"autores" => array:1 [
0 => array:3 [
"colaboracion" => "Grupo de Estudio de Enfermedad Invasora Neumocócica en el País Vasco y Navarra"
"etal" => false
"autores" => array:5 [
0 => "E. Bernaola"
1 => "J. De Aristegui"
2 => "M. Herranz"
3 => "C. García"
4 => "C. Fernández"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "An Esp Pediatr"
"fecha" => "2002"
"volumen" => "57"
"paginaInicial" => "301"
"paginaFinal" => "309"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/12392663"
"web" => "Medline"
]
]
]
]
]
]
]
]
27 => array:3 [
"identificador" => "bib0140"
"etiqueta" => "28."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Factores predictivos de enfermedad neumocócica invasora: estudio de casos y controles"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:6 [
0 => "C. Pérez"
1 => "G. Solís"
2 => "D. Miguel"
3 => "P. De la Iglesia"
4 => "G. Viejo de la Guerra"
5 => "M.A. Martín"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "An Esp Pediatr"
"fecha" => "2002"
"volumen" => "57"
"paginaInicial" => "310"
"paginaFinal" => "316"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/12392664"
"web" => "Medline"
]
]
]
]
]
]
]
]
28 => array:3 [
"identificador" => "bib0145"
"etiqueta" => "29."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Incidencia de la enfermedad invasiva por <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> en Sabadell y posible impacto de las nuevas vacunas antineumocócicas conjugadas"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:6 [
0 => "V. Pineda"
1 => "M. Domingo"
2 => "H. Larramona"
3 => "A. Pérez"
4 => "F. Segura"
5 => "D. Fontanals"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:5 [
"tituloSerie" => "Vacunas"
"fecha" => "2002"
"volumen" => "1"
"paginaInicial" => "13"
"paginaFinal" => "17"
]
]
]
]
]
]
29 => array:3 [
"identificador" => "bib0150"
"etiqueta" => "30."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Epidemiología de la meningitis producida por <span class="elsevierStyleItalic">Haemophilus influenzae</span> tipo b. <span class="elsevierStyleItalic">Neisseria meningitidis</span> y <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> en niños de la Comunidad Valenciana, España"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:6 [
0 => "A. Morant"
1 => "J. Díez"
2 => "C. Gimeno"
3 => "N. De la Muela"
4 => "I. Pereiró"
5 => "J. Brines"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Rev Neurol"
"fecha" => "1998"
"volumen" => "26"
"paginaInicial" => "34"
"paginaFinal" => "37"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/9533202"
"web" => "Medline"
]
]
]
]
]
]
]
]
30 => array:3 [
"identificador" => "bib0155"
"etiqueta" => "31."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "the Group for the Study of Invasive Diseases. Epidemiology of invasive <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> infections in children in Spain, 1996-1998"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:7 [
0 => "J. Díez"
1 => "I. Pereiró"
2 => "A. Morant"
3 => "C. Gimeno"
4 => "M. Lerma"
5 => "I. Oyagüez"
6 => "A. González"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "J Infect"
"fecha" => "2002"
"volumen" => "45"
"paginaInicial" => "139"
"paginaFinal" => "143"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/12387768"
"web" => "Medline"
]
]
]
]
]
]
]
]
31 => array:3 [
"identificador" => "bib0160"
"etiqueta" => "32."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "Geographical differences in invasive pneumococcal disease rates and serotype frequency in young children"
"autores" => array:1 [
0 => array:2 [
"etal" => false
"autores" => array:3 [
0 => "W.P. Hausdorff"
1 => "G.R. Silber"
2 => "P.R. Paradiso"
]
]
]
]
]
"host" => array:1 [
0 => array:2 [
"doi" => "10.1016/S0140-6736(00)04222-7"
"Revista" => array:6 [
"tituloSerie" => "Lancet"
"fecha" => "2001"
"volumen" => "357"
"paginaInicial" => "950"
"paginaFinal" => "952"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/11289365"
"web" => "Medline"
]
]
]
]
]
]
]
]
32 => array:3 [
"identificador" => "bib0165"
"etiqueta" => "33."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
"titulo" => "The epidemiology of invasive <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> disease in Catalonia (Spain). A hospital-base study"
"autores" => array:1 [
0 => array:2 [
"etal" => true
"autores" => array:6 [
0 => "A. Domínguez"
1 => "L. Salleras"
2 => "N. Cardeñosa"
3 => "P. Ciruela"
4 => "G. Carmona"
5 => "A. Martínez"
]
]
]
]
]
"host" => array:1 [
0 => array:1 [
"Revista" => array:6 [
"tituloSerie" => "Vaccine"
"fecha" => "2002"
"volumen" => "20"
"paginaInicial" => "2989"
"paginaFinal" => "2994"
"link" => array:1 [
0 => array:2 [
"url" => "https://www.ncbi.nlm.nih.gov/pubmed/12126912"
"web" => "Medline"
]
]
]
]
]
]
]
]
33 => array:3 [
"identificador" => "bib0170"
"etiqueta" => "34."
"referencia" => array:1 [
0 => array:2 [
"contribucion" => array:1 [
0 => array:2 [
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