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"correspondencia" => "<span class="elsevierStyleItalic">Correspondencia</span>: Dr. M. Caicoya. Servicio de Prevención de Riesgos Laborales. Hospital Monte Naranco. Avda. Doctores Fernández Vega 107. 33012 Oviedo. España"
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"titulo" => "Lung cancer and smoking in Asturias, Spain. A case-control study"
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0 => "Cáncer de pulmón"
1 => "Estudio de casos y controles"
2 => "Tabaco"
3 => "Edad"
4 => "Dosis-respuesta"
5 => "Efecto del abandono del tabaco"
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"resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Examinar la relación entre el consumo de tabaco y cáncer de pulmón en Asturias.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realizó un estudio de casos y controles de base hospitalaria. Los casos fueron pacientes con diagnóstico nuevo de cáncer de pulmón (casos incidentes) y los controles procedían de los servicios quirúrgicos. La información obtenida incluyó el consumo de tabaco, las exposiciones ocupacionales y las variables demográficas.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron en el análisis 197 casos y 196 controles. La odds ratio (OR) ajustada de cáncer de pulmón fue de 5,77 (intervalo de confianza [IC] del 95%, 2,96-11,22) para el consumo de cigarrillos. El riesgo aumentaba con la cantidad de cigarrillos fumados por día, el número de paquetes/ día, la edad de inicio del hábito, y disminuía con el número de años desde el abandono.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La relación entre el tabaco y el cáncer de pulmón en Asturias es similar a la encontrada en otros estudios llevados a cabo en el mundo occidental. La magnitud de la asociación puede explicar la frecuencia de cáncer de pulmón en Asturias.</p>"
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"resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Lung cancer in Asturias is 1.4-fold greater than the Spanish average, while the proportion of smokers is similar. The objective of this study was to examine the relationship between lung cancer and smoking in Asturias.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We performed a hospital-based, incident case control study. The cases were newly diagnosed lung cancer patients and controls were patients from the surgical wards. Information was sought on smoking, occupational exposures, and demographic variables. The analysis was performed by means of odds ratios (OR).</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">One hundred ninety-seven cases and 196 controls were included in the analysis. The adjusted OR of cigarette smoking was 5.77 (95% CI, 2.96-11.22). The risk increased with the number of cigarettes smoked per day (χ<span class="elsevierStyleSup">2</span> = 56.3), the number of packs/year (χ<span class="elsevierStyleSup">2</span> = 48.4), and the age at which smoking started (χ<span class="elsevierStyleSup">2</span> = 76.5). The OR diminished with the number of years of cessation (χ<span class="elsevierStyleSup">2</span> = 39.9).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The relationship between smoking and lung cancer in Asturias is similar to that found in other studies carried out in other parts of the western world. The magnitude of the OR may explain the frequency of lung cancer in Asturias. Greater efforts should be devoted to controlling this problem.</p>"
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