Methodology note
Application of two-part models and Cholesky decomposition to incorporate covariate-adjusted utilities in probabilistic cost-effectiveness models
Aplicación de los modelos en dos etapas y la descomposición de Cholesky para incorporar las utilidades ajustadas en los modelos probabilísticos de coste-efectividad
Arantzazu Arrospidea,b,c,
, Juan Manuel Ramos-Goñic,d,e, Petros Pechlivanoglouf,g, Javier Mara,b,c,h
Corresponding author
a Unidad de Investigación AP-OSIs, Hospital Alto Deba, Arrasate-Mondragón, Gipuzkoa, España
b Instituto de Investigación Sanitaria Biodonostia, San Sebastián, España
c Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), España
d EuroQol Research Foundation, Rotterdam, The Netherlands
e Axentiva Solutions, Tacoronte, Tenerife, España
f The Hospital for Sick Children, Toronto, Canada
g University of Toronto, Canada
h Unidad de Gestión Sanitaria, Hospital Alto Deba, Arrasate-Mondragón, Gipuzkoa, España
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