What is new?
Key points Grading of Recommendations Assessment, Development, and Evaluation (GRADE) offers a transparent and structured process to include resource use in the development of health care recommendations. Important differences in resource use should be included along with other important outcomes in evidence profiles and Summary of Findings tables. Key steps in considering resource use are the identification of resource use that is potentially important to decision makers, rating the confidence in effect estimates for important effects on resource use, and valuation of resource use in terms of costs for the specific setting for which ecommendations are being made.